Imidazolium salts

Claim 1

A quaternary imidazolium salt represented by the structure ##SPC18## and hydrates thereof, wherein A is a member selected from the group consisting of phenyl, mono-, di- and trihalophenyl, lower alkylphenyl, lower alkoxyphenyl, thienyl and halothienyl; B is a member selected from the group consisting of benzyl, mono-, di- and trihalobenzyl, mono- and di-lower alkylbenzyl, lower alkoxybenzyl, cyanobenzyl, phenethyl, mono-, di- and tri-halophenethyl, mono- and di-lower alkylphenethyl, lower alkoxyphenethyl, cyanophenethyl, mono- and di-nitrophenyl, mono- and di-aminophenyl, lower alkyl, lower alkenyl and lower alkynyl; D is selected from the group consisting of: a. an alkyl radical containing from 1 to 12 carbon atoms inclusive; b. a carbamoyl-alkyl radical represented by the formula ##SPC19## wherein R is selected from the group consisting of hydrogen and loweralkyl; each R 1 is independently selected from the group consisting of hydrogen, lower alkyl, halo, nitro, trifluoromethyl, lower alkoxy and phenoxy; a and m are integers of from 1 to 1 inclusive; and n is an integer of from 0 to 2 inclusive; c. an aroylalkyl radical represented by the formula ##EQU2## wherein Ar is selected from the group consisting of thienyl, halothienyl, phenyl, mono- and di-substituted phenyl and wherein each substituent in said substituted phenyl is selected independently from the group consisting of halo, lower alkyl and lower alkoxy; and p is an integer of from 1 to 4 inclusive; d. an aralkyl radical represented by the formula ##SPC20## wherein R 2 is selected from the group consisting of hydrogen, halo, lower alkyl, lower alkoxy, nitro and sulfamoyl; R 3 is selected from the group consisting of hydrogen, halo, lower alkyl, lower alkoxy and cyano; and p is an integer of from 1 to 4 inclusive; e. a diarylmethyl radical represented by the formula ##EQU3## wherein each Ar 1 is selected independently from the group consisting of phenyl and halophenyl; f. an arylaminoethyl radical represented by the formula ##SPC21## wherein each R 4 is independently selected from the group consisting of hydrogen, halo and lower alkyl; and a is an integer of from 1 to 2 inclusive; g. an arylether-alkyl radical represented by the formula -(CH.sub.2).sub.q --Q--Ar.sup.2 wherein Q is selected from the group consisting of oxygen and sulfur; Ar 2 is selected from the group consisting of phenyl, mono- and di-substituted phenyl and naphthyl, and wherein each substituent in said substituted phenyl is selected independently from the group consisting of halo, lower alkyl, lower alkoxy and allyl; and q is an integer of from 2 to 3 inclusive; h. a dihydrobenzofuranylmethyl radical represented by the formula ##SPC22## wherein R 5 is selected from the group consisting of hydrogen and halo; i. an aryl hydroxyethyl radical represented by the formula ##SPC23## wherein R 6 is selected from the group consisting of hydrogen, halo and lower alkoxy, and a is a integer of from 1 to 2 inclusive; k. a phenoxy-2-oxopropyl radical represented by the formula ##EQU4## wherein Ar 3 is selected from the group consisting of phenyl, halophenyl and dihalophenyl; and W is a pharmaceutically acceptable anion selected from the group consisting of chloride, bromide, iodide, methanesulfonate, p-toluenesulfonate, nitrate, sulfate, phosphate, acetate, propionate, glycolate, lactate, pyruvate, malonate, succinate, maleate, fumarate, malate, tartrate, citrate, benzoate, cinnamate, mandelate, ethanesulfonate, benzenesulfonate, cyclohexanesulfamate, salicylate and p-aminosalicylate.