US3991106A
Expired / Lapsed
US
⏱️ 0.0 years remaining
16-Ethers of 8-aza-9-dioxothia-11,12-seco-prostaglandins
Assignee: Merck and Co Inc
•
Filing: 1974-09-13
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Granted: 1976-11-09
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Expires: 1994-09-13
Abstract
Abstract The invention is concerned with novel 16-aryloxy-, 16-alkoxy-, 16-arylthio- and 16-alkylthio-8-aza-9-dioxothia-11,12-seco-prostaglandins and processes for their preparation. These novel compounds are useful as pharmaceuticals since they can be used in animals for estrus synchronization and treatment of infertility due to persistence of luteal function.
Inventors
- 👤 Edward J. Cragoe, Jr.
- 👤 James H. Jones
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 05:03
CPC Classifications
C; C07; C07D; C07D309/00; C07D309/02; C07D309/08; C07D309/10; C07D309/12; C07C; C07C45/00; C07C45/51; C07C45/511; C07C45/515; C07D303/00; C07D303/02; C07D303/36
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
21 words
The compound of the formula ##SPC4## wherein X is hydrogen, halogen, trifluoromethyl, loweralkyl, or loweralkoxy; and n is 1 or 2.
Claim 2
Dependent Claim
21 words
The compound of the formula ##SPC4## wherein X is hydrogen, halogen, trifluoromethyl, loweralkyl, or loweralkoxy; and n is 1 or 2.
Claim 3
Dependent Claim
9 words
The compound of claim 1 which is 7-{N-[4-hydroxy-5-(4-fluorophenoxy)pentyl]methanesulfonamido}-heptanoic acid.
Claim 4
Dependent Claim
9 words
The compound of claim 1 which is 7-{N-[4-hydroxy-5-(2-fluorophenoxy)pentyl]methanesulfonamido}-heptanoic acid.
Claim 5
Dependent Claim
9 words
The compound of claim 1 which is 7-{N-[4-hydroxy-5-(3-trifluoromethylphenoxy)pentyl]methanesulfonamido}heptanoic acid.
Claim 6
Dependent Claim
9 words
The compound of claim 1 which is 7-{N-[4-hydroxy-5-(3-chlorophenoxy)pentyl]methanesulfonamido}-heptanoic acid.
Claim 7
Dependent Claim
9 words
The compound of claim 1 which is 7-{N-[4-hydroxy-5-(4-methoxyphenoxy)pentyl]methanesulfonamido}-heptanoic acid.
Claim 8
Dependent Claim
9 words
The compound of claim 1 which is 7-[N-(4-hydroxy-5-phenoxypentyl)methanesulfonamido]heptanoic acid.
Claim 9
Dependent Claim
20 words
The compound of claim 1 wherein X is selected from bromo, iodo, chloro, methyl, ethyl, methoxy, fluoro, difluoro, and dichloro.
References Cited (Backward Citations)
US3541130A
Cited
US3793365A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-11-09 | 1980-05-10 | 1980-11-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-11-09 | 1984-05-10 | 1984-11-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-11-09 | 1988-05-10 | 1988-11-09 | $7700.00 | Window Closed / Lapsed |