US3989730A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Bone-seeking technetium-99m complex
Assignee: Research Corp
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Filing: 1973-06-11
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Granted: 1976-11-02
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Expires: 1993-06-11
Abstract
Abstract A bone-seeking, technetium-99m-tin-phosphonate complex effective as a skeletal-imaging agent has been found particularly useful for diagnostic purposes. Skeletal tissue concentrations of technetium-99m obtained with the complex compare favorably to other bone-seeking radionuclides.
Inventors
- 👤 Gopal Subramanian
- 👤 John Gilmore McAfee
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 18:16
CPC Classifications
A; A61; A61K; A61K51/00; A61K51/02; A61K51/04; A61K51/0489; A61K2123/00
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
10 words
A technetium-99m-tin-methylene diphosphonate complex useful as a bone-seeking skeletal-imaging agent.
Claim 2
Dependent Claim
10 words
A technetium-99m-tin-methylene diphosphonate complex useful as a bone-seeking skeletal-imaging agent.
Claim 3
Dependent Claim
8 words
A technetium-99m-tin-1-aminoethane-1,1-diphosphonate useful as a bone-seeking skeletal-imaging agent.
Claim 4
Dependent Claim
8 words
A technetium-99m-tin-1-aminoethane-1,1-diphosphonate useful as a bone-seeking skeletal-imaging agent.
Claim 5
Dependent Claim
34 words
A method for making the complex of claim 1 which comprises mixing in aqueous solution a non-toxic stannous salt, methylene diphosphonic acid or a non-toxic salt thereof and a non-toxic technetium-99m containing pertechnetate salt.
Claim 6
Dependent Claim
33 words
A method for making the complex of claim 2 which comprises mixing in aqueous solution a non-toxic stannous salt, 1-aminoethane-1,1-diphosphonic acid or a non-toxic salt thereof and a non-toxic technetium-99m containing pertechnetate salt.
References Cited (Backward Citations)
US3466361A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-11-02 | 1980-05-03 | 1980-11-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-11-02 | 1984-05-03 | 1984-11-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-11-02 | 1988-05-03 | 1988-11-02 | $7700.00 | Window Closed / Lapsed |