US3988450A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cephalosporins
Assignee: Beecham Group PLC
•
Filing: 1975-03-27
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Granted: 1976-10-26
•
Expires: 1995-03-27
Abstract
Abstract Cephalosporin analogues of the formula (I):
Inventors
- 👤 Brian George James
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 13:47
CPC Classifications
C; C07; C07D; C07D205/00; C07D205/02; C07D205/06; C07D205/08; C07D205/09
Claims Analysis
Total Claims: 27
Claim 1
Independent Claim
28 words
A cephalosporin analogue of the formula (IV): ##SPC70## or a pharmaceutically acceptable salt thereof wherein Z 1 is hydrogen or hydroxyl and Z 2 is hydrogen or chlorine.
Claim 2
Dependent Claim
28 words
A cephalosporin analogue of the formula (IV): ##SPC70## or a pharmaceutically acceptable salt thereof wherein Z 1 is hydrogen or hydroxyl and Z 2 is hydrogen or chlorine.
Claim 3
Dependent Claim
11 words
A compound according to claim 1 wherein Z 2 is hydrogen.
Claim 4
Dependent Claim
11 words
A compound according to claim 2 wherein Z 1 is hydrogen.
Claim 5
Dependent Claim
22 words
A salt of a compound according to claim 1 wherein the salt is the sodium, potassium, calcium, magnesium, aluminum or ammonium salt.
Claim 6
Dependent Claim
18 words
A salt of a compound according to claim 1 wherein the salt is the sodium or potassium salt.
Claim 7
Dependent Claim
10 words
The compound according to claim 1 which is 3-(o-carboxybenzyl)-7β-(D-α-phenylglycyl)amino-ceph-3-em-4-carboxylic acid.
Claim 8
Dependent Claim
10 words
The compound according to claim 1 which is 3-(m-carboxybenzyl)-7β-(D-α-phenylglycyl)amino-ceph-3-em-4-carboxylic acid.
Claim 9
Dependent Claim
10 words
The compound according to claim 1 which is 3-(p-carboxybenzyl)-7β-(D-α-phenylglycyl)amino-ceph-3-em-4-carboxylic acid.
Claim 10
Dependent Claim
31 words
A pharmaceutical composition useful for treating bacterial infections in humans and animals which comprises an anti-bacterially effective amount of a compound of claim 1 in combination with a pharmaceutically acceptable carrier.
Claim 11
Dependent Claim
11 words
A composition according to claim 9 wherein Z 2 is hydrogen.
Claim 12
Dependent Claim
11 words
A composition according to claim 10 wherein Z 1 is hydrogen.
Claim 13
Dependent Claim
31 words
A composition according to claim 10 wherein the compound is in the form of a salt selected from the group consisting of the sodium, potassium, calcium, magnesium, aluminum and ammonium salts.
Claim 14
Dependent Claim
16 words
A pharmaceutical composition according to claim 12 wherein the salt is the potassium or sodium salt.
Claim 15
Dependent Claim
13 words
A pharmaceutical composition according to claim 9 wherein the compound is 3-(o-carboxybenzyl)-7β-(D-α-phenylglycyl)amino-ceph-3-em-4-carboxylic acid.
Claim 16
Dependent Claim
13 words
A pharmaceutical composition according to claim 9 wherein the compound is 3-(m-carboxybenzyl)-7β-(D-α-phenyl-glycyl)amino-ceph-3-em-4-carboxylic acid.
Claim 17
Dependent Claim
13 words
A pharmaceutical composition according to claim 9 wherein the compound is 3-(p-carboxybenzyl)-7β-(D-α-phenylglycyl)amino-ceph-3-em-4-carboxylic acid.
Claim 18
Dependent Claim
11 words
A pharmaceutical composition according to claim 9 in injectable administration form.
Claim 19
Dependent Claim
31 words
A method of treating bacterial injections in humans and animals which comprises administering to a human or animal in need thereof an anti-bacterially effective amount of a compound of claim 1.
Claim 20
Dependent Claim
11 words
A method according to claim 18 wheren Z 2 is hydrogen.
Claim 21
Dependent Claim
11 words
A method according to claim 19 wherein Z 1 is hydrogen.
Claim 22
Dependent Claim
32 words
A method according to claim 18 wherein the compound is administered in the form of a salt selected from the group consisting of the sodium, potassium, calcium, magnesium, aluminum and ammonium salts.
Claim 23
Dependent Claim
15 words
A method according to claim 21 wherein the salt is the sodium or potassium salt.
Claim 24
Dependent Claim
12 words
A method according to claim 18 wherein the compound is 3-(o-carboxybenzyl)-7β-(D-α-phenylglycyl)amino-ceph-3-em-4-carboxylic acid.
Claim 25
Dependent Claim
12 words
A method according to claim 18 wherein the compound is 3-(m-carboxybenzyl)-7β-(D-α-phenylglycyl)amino-ceph-3-em-4-carboxylic acid.
Claim 26
Dependent Claim
12 words
A method according to claim 18 wherein the compound is 3-(p-carboxybenzyl)-7β-(D-α-phenylglycyl)amino-ceph-3-em-4-carboxylic acid.
Claim 27
Dependent Claim
12 words
A method according to claim 18 wherein the administration is by injection.
References Cited (Backward Citations)
US3769277A
Cited
US3849408A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-10-26 | 1980-04-26 | 1980-10-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-10-26 | 1984-04-26 | 1984-10-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-10-26 | 1988-04-26 | 1988-10-26 | $7700.00 | Window Closed / Lapsed |