US3988340A
Expired / Lapsed
US
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6-Alkoxymethyl-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones and 7-alkoxymethyl-6-[H]-1,2,3,4-tetrahydropyrimido[2,1-b]quinazolin-2-ones
Assignee: Bristol Myers Co
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Filing: 1975-01-23
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Granted: 1976-10-26
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Expires: 1995-01-23
Abstract
Abstract Optionally substituted 6-alkoxymethyl-1,2,3,5-tetrahydroimidazo[2,1-b]-quinazolin-2-ones and 7-alkoxymethyl-6-[H]-1,2,3,4-tetrahydropyrimido[2,1-b]-quinazolin-2-ones or the pharmaceutically acceptable salts thereof are compounds useful as blood platelet anti-aggregative and/or antihypertensive and/or bronchodilator agents in mammals, including humans.
Inventors
- 👤 Richard Anthony Partyka
- 👤 Warren Neil Beverung, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 16:53
CPC Classifications
C; C07; C07D; C07D487/00; C07D487/02; C07D487/04; C07C; C07C205/00; C07C205/49; C07C205/57; C07C205/58; C07C205/59; C07C205/60
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
61 words
A compound having the formula ##SPC44## in which R 1 is H, phenyl or (lower)alkyl, R is (lower)alkyl, R 2 is hydrogen, chloro, bromo, fluoro, CF 3 , hydroxy, (lower)alkyl of 1 to 3 carbon atoms or (lower)alkoxy of 1 to 3 carbon atoms and n is an integer of 1 or 2; or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
61 words
A compound having the formula ##SPC44## in which R 1 is H, phenyl or (lower)alkyl, R is (lower)alkyl, R 2 is hydrogen, chloro, bromo, fluoro, CF 3 , hydroxy, (lower)alkyl of 1 to 3 carbon atoms or (lower)alkoxy of 1 to 3 carbon atoms and n is an integer of 1 or 2; or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
64 words
A compound of claim 1 having the formula ##SPC45## in which R 1 is H, phenyl or (lower)alkyl, R is (lower)alkyl, R 2 is hydrogen, chloro, bromo, fluoro, CF 3 , hydroxy, (lower)alkyl of 1 to 3 carbon atoms or (lower)alkoxy of 1 to 3 carbon atoms and n is an integer of 1 or 2; or a pharmaceutically acceptable acid addition salt thereof.
Claim 4
Dependent Claim
55 words
A compound of claim 2 having the formula ##SPC46## in which R 1 is H, phenyl or (lower)alkyl, R is (lower)alkyl, R 2 is hydrogen, chloro, bromo, CF 3 , fluoro, hydroxy, (lower)alkyl of 1 to 3 carbon atoms or (lower)alkoxy of 1 to 3 carbon atoms, or a pharmaceutically acceptable acid addition salt thereof.
Claim 5
Dependent Claim
48 words
A compound of claim 2 having the formula ##SPC47## in which R is (lower)alkyl, R 2 is hydrogen, chloro, bromo, fluoro, CF 3 , hydroxy, (lower)alkoxy of 1 to 3 carbon atoms or (lower)alkyl of 1 to 3 carbon atoms; or a pharmaceutically acceptable acid addition salt thereof.
Claim 6
Dependent Claim
51 words
A compound of claim 2 having the formula ##SPC48## in which R is (lower)alkyl of 1 to 3 carbon atoms, R 2 is H, hydroxy, (lower)alkoxy of 1 to 3 carbon atoms or (lower)alkyl of 1 to 3 carbon atoms, chloro, or fluoro; or a pharmaceutically acceptable acid addition salt thereof.
Claim 7
Dependent Claim
25 words
A compound of claim 2 having the formula ##SPC49## in which R 2 is H, Cl, methoxy, methyl or hydroxy; or the hydrochloride salt thereof.
Claim 8
Dependent Claim
16 words
The compound of claim 6 in which R 2 is methoxy; or the hydrochloride salt thereof.
Claim 9
Dependent Claim
16 words
The compound of claim 6 in which R 2 is methyl; or the hydrochloride salt thereof.
Claim 10
Dependent Claim
14 words
The compound having the formula ##SPC50## or a pharmaceutically acceptable acid addition salt thereof.
Claim 11
Dependent Claim
14 words
The compound having the formula ##SPC50## or a pharmaceutically acceptable acid addition salt thereof.
Claim 12
Dependent Claim
9 words
The hydrochloride salt of the compound of claim 9.
Claim 13
Dependent Claim
14 words
The compound having the formula ##SPC51## or a pharmaceutically acceptable acid addition salt thereof.
Claim 14
Dependent Claim
14 words
The compound having the formula ##SPC51## or a pharmaceutically acceptable acid addition salt thereof.
Claim 15
Dependent Claim
9 words
The hydrochloride salt of the compound of claim 11.
Claim 16
Dependent Claim
14 words
The compound having the formula ##SPC52## or a pharmaceutically acceptable acid addition salt thereof.
Claim 17
Dependent Claim
14 words
The compound having the formula ##SPC52## or a pharmaceutically acceptable acid addition salt thereof.
Claim 18
Dependent Claim
9 words
The hydrochloride salt of the compound of claim 13.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-10-26 | 1980-04-26 | 1980-10-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-10-26 | 1984-04-26 | 1984-10-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-10-26 | 1988-04-26 | 1988-10-26 | $7700.00 | Window Closed / Lapsed |