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US3987391A Expired / Lapsed US ⏱️ 0.0 years remaining

Method and apparatus for correcting total particle volume error due to particle coincidence

Assignee: Coulter Electronics Inc
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Filing: 1974-12-02
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Granted: 1976-10-19
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Expires: 1994-12-02
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Abstract

Abstract In an apparatus which develops output signal data, a portion of a liquid containing particles is caused to flow through a sensing zone. Ideally the particles go through one at a time. Each particle sensed generates a particle signal having an amplitude proportional to the size or volume of the particle. The particle signal is utilized for producing the output signal data. The output signal data is a measure of the total volume of particulate matter in a quantity of liquid containing particles and is subject to error due to the occasional simultaneous presence of particles in the sensing zone which is termed coincidence. An error correction signal is also developed by the apparatus which varies in accordance with the repetition rate of particles passing through the sensing zone. The error correction signal is employed to correct the output signal data which is subject to error due to particle coincidence.

Inventors

  • 👤 Walter R. Hogg

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 21:44
CPC Classifications
G; G01; G01N; G01N15/00; G01N15/10; G01N15/1031; G01N15/12; G01N15/131; G01N15/132

Claims Analysis

Total Claims: 23
Claim 1
Independent Claim 179 words
A method of ascertaining the total volume of particulate matter suspended in a quantity of liquid and for correcting error in ascertaining said total volume including the steps of: A. passing the quantity of liquid through a sensing zone where each particle generates a particle signal having an amplitude which is directly proportional to the size of the individual particle sensed, B. converting each signal into an electrical quantity which is directly related to the amplitude of said signal without regard to its duration and which is capable of being accumulated, C. accumulating all of the electrical quantities generated by particles sensed in said quantity of liquid, D. deriving at least one output which is proportional to the total accumulated electrical quantities and hence also is proportional to the total volume of particulate matter so suspended in said quantity of liquid, E. developing an error correction signal having an amplitude which varies in accordance with the repetition rate of the particles passing through the sensing zone, and F. varying the output signal in accordance with said error correction signal.
Claim 2
Independent Claim 179 words
A method of ascertaining the total volume of particulate matter suspended in a quantity of liquid and for correcting error in ascertaining said total volume including the steps of: A. passing the quantity of liquid through a sensing zone where each particle generates a particle signal having an amplitude which is directly proportional to the size of the individual particle sensed, B. converting each signal into an electrical quantity which is directly related to the amplitude of said signal without regard to its duration and which is capable of being accumulated, C. accumulating all of the electrical quantities generated by particles sensed in said quantity of liquid, D. deriving at least one output which is proportional to the total accumulated electrical quantities and hence also is proportional to the total volume of particulate matter so suspended in said quantity of liquid, E. developing an error correction signal having an amplitude which varies in accordance with the repetition rate of the particles passing through the sensing zone, and F. varying the output signal in accordance with said error correction signal.
Claim 3
Dependent Claim 56 words
The method of claim 1 wherein the step of developing said error correction signal includes the step of developing a repetition rate signal which varies in amplitude in accordance with the repetition rate of particle signals and coupling said repetition rate signal to said accumulating means for a predetermined period in response to each particle pulse.
Claim 4
Dependent Claim 16 words
The method of claim 2 in which said predetermined period is a function of particle size.
Claim 5
Dependent Claim 91 words
The method of claim 1 wherein said step of developing an error correction signal includes: A. developing a first signal in response to each particle pulse having a duration related to the particle pulse amplitude, B. converting said repitition rate signal into a second electrical quantity which is capable of being accumulated, said quantity varying in amplitude in accordance with said repetition rate signal and having a duration substantially equal to said first signal duration, and C. accumulating said second electrical quantities with said electrical quantities for varying said output signal.
Claim 6
Dependent Claim 66 words
The method of claim 4 wherein the step of developing said first signal includes the step of: A. measuring the maximum amplitude of each particle pulse, B. developing said first signal in response to passage of each pulse, C. integrating each said first signal to develop an integration signal, D. terminating said first signal when said integration signal exceeds said maximum amplitude of said particle pulse.
Claim 7
Dependent Claim 158 words
In an apparatus for providing output signal data representing the total volume of particulate matter in a quantity of liquid wherein a portion of the liquid is caused to flow through a sensing zone and each particle sensed generates a particle signal having an amplitude proportional to the size of the particle, which particle signal is utilized for producing the output signal data, and wherein said output signal data is accumulated in an accumulation means and is subject to error due to coincidence of particles in the sensing zone, the improvement comprising, error correction means operative to vary in a predetermined manner the output signal data to correct said data for total volume error due to coincidence of particles, said error correction means including rate detection means operative to develop a repetition rate signal varying in amplitude in accordance with the repetition rate of said particles, said output signal data varying in accordance with said repetition rate signal.
Claim 8
Dependent Claim 158 words
In an apparatus for providing output signal data representing the total volume of particulate matter in a quantity of liquid wherein a portion of the liquid is caused to flow through a sensing zone and each particle sensed generates a particle signal having an amplitude proportional to the size of the particle, which particle signal is utilized for producing the output signal data, and wherein said output signal data is accumulated in an accumulation means and is subject to error due to coincidence of particles in the sensing zone, the improvement comprising, error correction means operative to vary in a predetermined manner the output signal data to correct said data for total volume error due to coincidence of particles, said error correction means including rate detection means operative to develop a repetition rate signal varying in amplitude in accordance with the repetition rate of said particles, said output signal data varying in accordance with said repetition rate signal.
Claim 9
Dependent Claim 65 words
The apparatus of claim 6 wherein said error correction means is operative to develop a correction signal varying in amplitude in accordance with the size and repetition rate of said particle signals, said accumulation means being coupled to said error correction means and responsive to said correction signal to vary said output signal data to correct for total volume error due to coincidence of particles.
Claim 10
Dependent Claim 19 words
The apparatus of claim 7 wherein said accumulation means sums said output signal data and said error correction signal.
Claim 11
Dependent Claim 61 words
The apparatus of claim 6 wherein said control means coupled to said rate detection means and operative in response to said particle pulses and said repetition rate signal to develop a correction signal, said accumulation means being coupled to said control means and responsive to said repetition rate signal to vary said output signal data to correct for total volume error.
Claim 12
Dependent Claim 66 words
The apparatus of claim 9 wherein said control means includes, pulse amplitude means responsive to each particle signal to generate a duration signal having a duration related to said particle signal amplitude, said control means operative in response to said duration signal to develop said correction signal having an amplitude related to the amplitude of said repetition rate signal and a duration of said duration signal.
Claim 13
Dependent Claim 77 words
The apparatus of claim 10 wherein said pulse amplitude means includes maximum amplitude determining means coupled to said sensing zone and operative to develop a maximum amplitude signal related to the maximum amplitude of each particle signal, timing means coupled to said maximum amplitude determining means and operative in response to passage of each particle pulse to develop said duration signal having a duration which varies in accordance with the maximum amplitude of said maximum amplitude signal.
Claim 14
Dependent Claim 15 words
The apparatus of claim 11 wherein said maximum amplitude determining means is a pulse stretcher.
Claim 15
Dependent Claim 101 words
The apparatus of claim 11 wherein said timing means includes circuit means coupled to said maximum amplitude determining means and operative in response to passage of each particle pulse to develop said duration signal, integration means coupled to said circuit means and operative to integrate said duration signal and develop an integration signal, comparison means coupled to said integration means, and maximum amplitude determining means and operative in response to said integration signal exceeding said maximum amplitude signal to develop a termination signal for resetting said circuit means integration means and maximum amplitude determining means whereby said duration signal is terminated.
Claim 16
Dependent Claim 56 words
The apparatus of claim 13 wherein said control means include switch means coupled to said rate detection means and said timing means and operative in response to said repetition rate signal amplitude to develop said correction signal having an amplitude related to the amplitude of said repetition rate signal and a duration of said duration signal.
Claim 17
Dependent Claim 55 words
The apparatus of claim 13 wherein said circuit means include a trailing edge detector operative in response to the trailing edge of each particle pulse to develop a trailing edge signal, and a bistable multivibrator coupled to said trailing edge detector and operative in response to said trailing edge signal to develop said duration signal.
Claim 18
Dependent Claim 229 words
Apparatus for producing output signal data representing the total volume of particulate matter in a quantity of liquid containing said particulate matter, utilizing the output signals from a particle analyzing device wherein the quantity of liquid containing said particulate matter is caused to flow through a sensing zone including an electric current path of small dimensions wherein each particle sensed generates a particle signal having an amplitude proportional to the size of the particle sensed, said apparatus comprising: A. means for converting each signal as it occurs into an electrical quantity directly proportional to the amplitude of said signal without regard to its duration and capable of being accumulated, B. means for accumulating said quantities, C. means responsive to the total accumulated quantity providing an output signal proportional to said total quantity, D. means for controlling the operation of said accumulation means, and E. error correction means operative in a predetermined manner to vary the output signal to correct said output signal for its total volume error due to coincidence of particles, said error correction means including rate detection means coupled to said means for converting each signal as it occurs into an electrical quantity and being operative to develop a repetition rate signal which varies in amplitude in accordance with the repetition rate of particle signals, said output signal varying in accordance with said repetition rate signal amplitude.
Claim 19
Dependent Claim 229 words
Apparatus for producing output signal data representing the total volume of particulate matter in a quantity of liquid containing said particulate matter, utilizing the output signals from a particle analyzing device wherein the quantity of liquid containing said particulate matter is caused to flow through a sensing zone including an electric current path of small dimensions wherein each particle sensed generates a particle signal having an amplitude proportional to the size of the particle sensed, said apparatus comprising: A. means for converting each signal as it occurs into an electrical quantity directly proportional to the amplitude of said signal without regard to its duration and capable of being accumulated, B. means for accumulating said quantities, C. means responsive to the total accumulated quantity providing an output signal proportional to said total quantity, D. means for controlling the operation of said accumulation means, and E. error correction means operative in a predetermined manner to vary the output signal to correct said output signal for its total volume error due to coincidence of particles, said error correction means including rate detection means coupled to said means for converting each signal as it occurs into an electrical quantity and being operative to develop a repetition rate signal which varies in amplitude in accordance with the repetition rate of particle signals, said output signal varying in accordance with said repetition rate signal amplitude.
Claim 20
Dependent Claim 67 words
The apparatus of claim 16 wherein said error correction means include control means coupled to said rate detection means and operative in response to said particle pulses and said repetition rate signals to develop error correction signals, said means for accumulating said quantities being coupled to said control means and responsive to said correction signal to vary said output signal data to correct for total volume error.
Claim 21
Dependent Claim 66 words
The apparatus of claim 16 wherein said control means includes, pulse amplitude means responsive to each particle signal to generate a duration signal having a duration related to said particle signal amplitude, said control means operative in response to said duration signal to develop said correction signal having an amplitude related to the amplitude of said reptitition rate signal and a duration of said duration signal.
Claim 22
Dependent Claim 28 words
The apparatus of claim 16 wherein said quantity of liquid containing said particulate matter is a quantity of liquid containing a predetermined number of particles to be sensed.
Claim 23
Dependent Claim 20 words
The apparatus of claim 16 wherein said quantity of liquid containing said particulate matter is a predetermined volume of liquid.

References Cited (Backward Citations)

US3473010A Cited
US3439267A Cited
US3737633A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-10-19 1980-04-19 1980-10-19 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-10-19 1984-04-19 1984-10-19 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-10-19 1988-04-19 1988-10-19 $7700.00 Window Closed / Lapsed

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