US3987199A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Substituted benzenesulfonamides as anthelmintics
Assignee: Merck and Co Inc
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Filing: 1974-05-22
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Granted: 1976-10-19
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Expires: 1994-05-22
Abstract
Abstract This invention relates to a novel method for the treatment of parasitic diseases and the compositions used in said treatment. More specifically this invention relates to benzenesulfonamides substituted at the 3, 4, and 5 positions of the benzene ring and to the use of such compounds for the treatment of mature and immature liver fluke infections.
Inventors
- 👤 Helmut H. Mrozik
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 19:54
CPC Classifications
C; C07; C07C; C07C311/00; C07C311/15; C07C311/16; C07C309/00; C07C309/78; C07C309/86; C07C311/30; C07C311/37; C07C311/38; C07C311/39
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
68 words
A method for the treatment of mature and immature liver fluke infections which comprises administering to an animal with mature or immature liver fluke infections, an amount, therapeutically effective against mature and immature liver fluke, of a compound having the formula: ##SPC3## wherein R is hydrogen; X 1 and X 2 are each halogen, trifluoromethyl or nitro; and R 1 and R 2 are each hydrogen or loweralkyl.
Claim 2
Independent Claim
68 words
A method for the treatment of mature and immature liver fluke infections which comprises administering to an animal with mature or immature liver fluke infections, an amount, therapeutically effective against mature and immature liver fluke, of a compound having the formula: ##SPC3## wherein R is hydrogen; X 1 and X 2 are each halogen, trifluoromethyl or nitro; and R 1 and R 2 are each hydrogen or loweralkyl.
Claim 3
Dependent Claim
25 words
The method of claim 1 in which the compound is orally administered in an amount of from 1 to 300 mg/kg of animal body weight.
Claim 4
Dependent Claim
25 words
The method of claim 2 in which the compound is orally administered in an amount of from 10 to 100 mg/kg of animal body weight.
Claim 5
Dependent Claim
15 words
The method of claim 1 in which X 1 and X 2 are both bromine.
Claim 6
Dependent Claim
12 words
The method of claim 4 in which the compound administered is 3,5-dibromobenzenesulfonamide.
Claim 7
Dependent Claim
15 words
The method of claim 1 in which X 1 and X 2 are both trifluoromethyl.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-10-19 | 1980-04-19 | 1980-10-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-10-19 | 1984-04-19 | 1984-10-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-10-19 | 1988-04-19 | 1988-10-19 | $7700.00 | Window Closed / Lapsed |