US3986952A
Expired / Lapsed
US
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Isolation of utero-evacuant substances from plant extracts
Assignee: Ortho Pharmaceutical Corp
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Filing: 1975-11-17
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Granted: 1976-10-19
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Expires: 1995-11-17
Abstract
Abstract A method of obtaining utero-evacuant substances from the zoapatle plant is described. The method involves the isolation and purification of biologically active compounds from the zoapatle plant by chromatography over silicic acid impregnated with silver nitrate.
Inventors
- 👤 Ramesh M. Kanojia
- 👤 Richard E. Huettemann
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 17:02
CPC Classifications
B; B01; B01D; B01D15/00; B01D15/08; A; A61; A61K; A61K36/00; A61K36/18; A61K36/185; A61K36/28; A61P; A61P15/00; A61P15/04; B01J; B01J20/00; B01J20/281; B01J20/282; B01J20/283; B01J20/30; B01J20/32; B01J20/3231; B01J20/3234; B01J20/3236
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
59 words
The method of purifying extracts containing materials obtained from the zoapatle plant which comprises the steps of: dissolving the mixture of semi-purified materials in a water-immiscible organic solvent, chromatographing the resultant solution on silicic acid impregnated with silver nitrate, eluting the silicic acid with a mixture of polar and non-polar organic solvents and collecting the fractions containing the materials.
Claim 2
Independent Claim
59 words
The method of purifying extracts containing materials obtained from the zoapatle plant which comprises the steps of: dissolving the mixture of semi-purified materials in a water-immiscible organic solvent, chromatographing the resultant solution on silicic acid impregnated with silver nitrate, eluting the silicic acid with a mixture of polar and non-polar organic solvents and collecting the fractions containing the materials.
Claim 3
Dependent Claim
15 words
The method of claim 1 wherein the zoapatle plant is Montanoa tomentosa or Montanoa floribunda.
Claim 4
Dependent Claim
22 words
The method of claim 1 wherein the water-immiscible solvent is selected from an aromatic hydrocarbon, a chlorinated hydrocarbon or an aliphatic ether.
Claim 5
Dependent Claim
16 words
The method of claim 3 wherein the organic solvent is selected from benzene, chloroform and ether.
Claim 6
Dependent Claim
17 words
The method of claim 1 wherein the silicic acid is impregnated with from 1-30% of silver nitrate.
Claim 7
Dependent Claim
20 words
The method of claim 1 wherein the mixture of polar and non-polar solvents comprises a mixture of acetone and benzene.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-10-19 | 1980-04-19 | 1980-10-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-10-19 | 1984-04-19 | 1984-10-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-10-19 | 1988-04-19 | 1988-10-19 | $7700.00 | Window Closed / Lapsed |