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US3985892A Expired / Lapsed US ⏱️ 0.0 years remaining

Pharmaceutical preparation for percutaneous treatment of local edemas employing acetazolamide

Assignee: Jouveinal SA
•
Filing: 1975-01-27
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Granted: 1976-10-12
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Expires: 1995-01-27
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Abstract

Abstract Method for percutaneous treatment of edemas of humans to reduce their swelling, by percutaneous application of a pharmaceutical preparation comprising an active element consisting of acetazolamide in a concentration of between 1 to 50% incorporated in a vehicle which is compatible with percutaneous administration.

Inventors

  • 👤 Claude P. Roux
  • 👤 Dieran Robert Torossian

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-29 22:13
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/41

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 60 words
A pharmaceutical composition for local external cutaneous treatment of a local subcutaneous edema of a human, the composition comprising a suspension for skin use consisting of the following: 10 parts of acetazolamide (5-acetamido-1,3,4-thiadiazole-2-sulfonamide), 10 parts of polyethylene glycol 300, 5 parts of stearic acid, 3.5 parts of liquid petrolatum, 3 parts of ascorbyl palmitate and 100 parts of water q.s.p.
Claim 2
Dependent Claim 60 words
A pharmaceutical composition for local external cutaneous treatment of a local subcutaneous edema of a human, the composition comprising a suspension for skin use consisting of the following: 10 parts of acetazolamide (5-acetamido-1,3,4-thiadiazole-2-sulfonamide), 10 parts of polyethylene glycol 300, 5 parts of stearic acid, 3.5 parts of liquid petrolatum, 3 parts of ascorbyl palmitate and 100 parts of water q.s.p.
Claim 3
Dependent Claim 53 words
A skin cream for local external cutaneous treatment of a local subcutaneous edema of a human, the skin cream comprising: 10 parts of acetazolamide (5-acetamido-1,3,4-thiadiazole-2-sulfonamide), 10 parts of poly-oxy-ethylene glycerides, 10 parts of polyethylene glycol stearate 300, 0.07 parts of methyl para-hydroxybenzoate, 0.04 parts of propyl para-hydroxybenzoate and 100 parts of water q.s.p.
Claim 4
Dependent Claim 53 words
A skin cream for local external cutaneous treatment of a local subcutaneous edema of a human, the skin cream comprising: 10 parts of acetazolamide (5-acetamido-1,3,4-thiadiazole-2-sulfonamide), 10 parts of poly-oxy-ethylene glycerides, 10 parts of polyethylene glycol stearate 300, 0.07 parts of methyl para-hydroxybenzoate, 0.04 parts of propyl para-hydroxybenzoate and 100 parts of water q.s.p.
Claim 5
Independent Claim 69 words
A method for cutaneous local treatment of a local subcutaneous edema of a human which method comprises applying to the skin over the edema a pharmaceutical composition which comprises: a pharmaceutical carrier compatible with cutaneous external application, a diuretic agent capable of passing the epidermal barrier incorporated in the pharmaceutical carrier; said agent being acetazolamide (5-acetamido-1,3,4-thiadiazole -2-sulfonamide), with a range of concentration being between 1% and 50% by weight.
Claim 6
Independent Claim 69 words
A method for cutaneous local treatment of a local subcutaneous edema of a human which method comprises applying to the skin over the edema a pharmaceutical composition which comprises: a pharmaceutical carrier compatible with cutaneous external application, a diuretic agent capable of passing the epidermal barrier incorporated in the pharmaceutical carrier; said agent being acetazolamide (5-acetamido-1,3,4-thiadiazole -2-sulfonamide), with a range of concentration being between 1% and 50% by weight.
Claim 7
Independent Claim 69 words
A method for cutaneous local treatment of a local subcutaneous edema of a human which method comprises applying to the skin over the edema a pharmaceutical composition which comprises: an emulsified pharmaceutical carrier compatible with cutaneous external application, a diuretic agent capable of passing the epidermal barrier incorporated in the pharmaceutical carrier; said agent being acetazolamide (5-acetamido-1,3,4,-thiadiazole-2-sulfonamide), with a range of concentration being between 1 and 50% by weight.
Claim 8
Independent Claim 69 words
A method for cutaneous local treatment of a local subcutaneous edema of a human which method comprises applying to the skin over the edema a pharmaceutical composition which comprises: an emulsified pharmaceutical carrier compatible with cutaneous external application, a diuretic agent capable of passing the epidermal barrier incorporated in the pharmaceutical carrier; said agent being acetazolamide (5-acetamido-1,3,4,-thiadiazole-2-sulfonamide), with a range of concentration being between 1 and 50% by weight.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-10-12 1980-04-12 1980-10-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-10-12 1984-04-12 1984-10-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-10-12 1988-04-12 1988-10-12 $7700.00 Window Closed / Lapsed

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