US3985871A
Expired / Lapsed
US
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Pharmaceutical heparinoidic factor-containing composition and therapeutic use thereof
Assignee: FINANZIARIA CRINOS SpA
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Filing: 1975-03-26
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Granted: 1976-10-12
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Expires: 1995-03-26
Abstract
Abstract A pharmaceutical composition comprising an anhydrous suspension of a heparinoidic factor in a suspending medium selected from vegetable and animal fats, aliphatic acids and their alkyl esters, in the presence of an anionic dispersant (typically sodium taurocholate), is orally administrable to patients in need of a medicine having antiplasmin inhibiting effect.
Inventors
- 👤 Adriano Butti
- 👤 Giuseppe Prino
- 👤 Marisa Mantovani
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 23:39
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/4841; A61K9/4858; A61K31/00; A61K31/70; A61K31/715
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
88 words
An orally administrable therapeutic composition producing an antiplasmin inhibiting effect, comprising an anhydrous suspension of: 1. an effective amount to inhibit antiplasmin of a heparinoidic factor in 2. a suspending medium consisting of vegetable and animal fats selected from the group consisting of olive oil, peanut oil, coconut oil, corn oil, tributyrin and commercial grade axunge, saturated and unsaturated aliphatic acids selected from the group consisting of arachidonic acid, linoleic acid, linolenic acid, oleic acid, actanoic acid, and alkyl esters thereof, or mixtures thereof, in the presence of
Claim 2
Dependent Claim
88 words
An orally administrable therapeutic composition producing an antiplasmin inhibiting effect, comprising an anhydrous suspension of: 1. an effective amount to inhibit antiplasmin of a heparinoidic factor in 2. a suspending medium consisting of vegetable and animal fats selected from the group consisting of olive oil, peanut oil, coconut oil, corn oil, tributyrin and commercial grade axunge, saturated and unsaturated aliphatic acids selected from the group consisting of arachidonic acid, linoleic acid, linolenic acid, oleic acid, actanoic acid, and alkyl esters thereof, or mixtures thereof, in the presence of
Claim 3
Dependent Claim
46 words
at least 0.1 parts by weight based on the heparinoidic factor of an anionic dispersant selected from the group consisting of sodium taurocholate, sodium glycolate, sodium cholate, sodium laurylsulfate, dioctyl sodium sulfosuccinate, alkyl aryl sulfate, fatty acid-saccharose esters, polyoxyethylene sorbitan monolaurate, mannite monooleate, and polysorbate 20.
Claim 4
Dependent Claim
46 words
at least 0.1 parts by weight based on the heparinoidic factor of an anionic dispersant selected from the group consisting of sodium taurocholate, sodium glycolate, sodium cholate, sodium laurylsulfate, dioctyl sodium sulfosuccinate, alkyl aryl sulfate, fatty acid-saccharose esters, polyoxyethylene sorbitan monolaurate, mannite monooleate, and polysorbate 20.
Claim 5
Dependent Claim
19 words
The composition of claim 1, wherein the heparinoidic factor is selected from the group consisting of HPF-1 and HPF-2.
Claim 6
Dependent Claim
9 words
The composition of claim 1 in unit dosage form.
Claim 7
Dependent Claim
32 words
A therapeutic method of treating a patient in need of an antiplasmin inhibiting composition, which comprises orally administering to said patient an antiplasmin inhibiting effective amount of the composition of claim 1.
Claim 8
Dependent Claim
27 words
The composition of claim 1 wherein said anionic dispersant is present in amounts between about 0.2 and about 0.5 parts by weight per part of heparinoidic factor.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-10-12 | 1980-04-12 | 1980-10-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-10-12 | 1984-04-12 | 1984-10-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-10-12 | 1988-04-12 | 1988-10-12 | $7700.00 | Window Closed / Lapsed |