US3984413A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Phenoxyalkanecarboxylic acid esters of hydroxyalkyltheophyllines and method for their manufacture
Assignee: Ludwig Merckle GmbH and Co KG Chem Pharm Fabrik
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Filing: 1974-02-21
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Granted: 1976-10-05
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Expires: 1994-02-21
Abstract
Abstract Phenoxyalkanecarboxylic acids are esterified with 7-(2-hydroxyethyl) theophylline or 7-(2,3-dihydroxypropyl) theophylline. The resulting esters have excellent antilipemic and anticholesterolemic properties as well as pronounced peripheral and vasodilative effect.
Inventors
- 👤 Gunter Metz
- 👤 Manfred Specker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 18:10
CPC Classifications
C; C07; C07D; C07D473/00; C07D473/02; C07D473/04; C07D473/06; C07D473/08
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
70 words
A phenoxy alkane carboxylic acid ester of an hydroxyalkyltheophylline of the formula ##SPC4## where R 1 is H or Q and Q is ##SPC5## in which X represents halogen or trifluoromethyl; R 2 represents hydrogen, straight-chain or branched alkyl having 1 to 5 carbon atoms or halophenoxy; R 3 represents hydrogen or straight-chain or branched alkyl having 1 to 5 carbon atoms and n has the value zero or unity.
Claim 2
Dependent Claim
70 words
A phenoxy alkane carboxylic acid ester of an hydroxyalkyltheophylline of the formula ##SPC4## where R 1 is H or Q and Q is ##SPC5## in which X represents halogen or trifluoromethyl; R 2 represents hydrogen, straight-chain or branched alkyl having 1 to 5 carbon atoms or halophenoxy; R 3 represents hydrogen or straight-chain or branched alkyl having 1 to 5 carbon atoms and n has the value zero or unity.
Claim 3
Dependent Claim
21 words
The ester of claim 1 where n is zero, R 2 and R 3 are CH 3 and X is p-Cl.
Claim 4
Dependent Claim
23 words
The ester of claim 1 where n is 1, R 1 , R 2 and R 3 are H and X is p-Cl.
Claim 5
Dependent Claim
24 words
The ester of claim 1 where n is 1, R 1 is Q, R 2 and R 3 are H and X is p-Cl.
Claim 6
Dependent Claim
21 words
The ester of claim 1 where n is 0, R 2 is p-chlorophenoxy, R 3 is H and X is p-Cl.
Claim 7
Dependent Claim
20 words
The ester of claim 1 where n is 0, R 2 and R 3 are H and X is p-Cl.
Claim 8
Dependent Claim
23 words
The ester of claim 1 where n is 0, R 2 is CH 3 , R 3 is H and X is p-Cl.
Claim 9
Dependent Claim
21 words
The ester of claim 1 where n = 0, R 2 and R 3 are CH 3 and X is o-Cl.
Claim 10
Dependent Claim
25 words
The ester of claim 1 where n = 0, R 2 is CH 3 , R 3 is H and X is m-CF 3 .
Claim 11
Dependent Claim
20 words
The ester of claim 1 where n = 0, R 2 and R 3 are H and X is p-I.
Claim 12
Dependent Claim
20 words
The ester of claim 1 where n = 0, R 2 and R 3 are H and X is p-F.
Claim 13
Dependent Claim
20 words
The ester of claim 1 where n = 0, R 2 and R 3 are H and X is p-Br.
References Cited (Backward Citations)
DE1106327B
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-10-05 | 1980-04-05 | 1980-10-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-10-05 | 1984-04-05 | 1984-10-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-10-05 | 1988-04-05 | 1988-10-05 | $7700.00 | Window Closed / Lapsed |