US3981874A
Expired / Lapsed
US
⏱️ 0.0 years remaining
N-[(Methoxymethyl-furyl)-methyl]-morphinans or -6,7-benzomorphans and salts thereof
Assignee: Boehringer Ingelheim GmbH
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Filing: 1974-10-15
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Granted: 1976-09-21
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Expires: 1994-10-15
Abstract
Abstract Compound of the formula WHEREIN R1 and R2, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 3 carbon atoms, R3 is hydrogen or methyl, R4 is R5 is hydrogen, methyl or acetyl, AND NON-TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF; THE COMPOUNDS AS WELL AS THEIR SALTS ARE USEFUL AS ANALGESICS.
Inventors
- 👤 Herbert Merz
- 👤 Adolf Langbein
- 👤 Gerhard Walther
- 👤 Klaus Stockhaus
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 13:41
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61P; A61P25/00; A61P25/04
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
47 words
A compound of the formula ##SPC22## wherein R 1 is methyl, ethyl or propyl, R 2 is hydrogen, methyl or ethyl, R 3 is hydrogen or methyl, R 4 is ##SPC23## R 5 is hydrogen, methyl or acetyl, or a non-toxic, pharmacologically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
47 words
A compound of the formula ##SPC22## wherein R 1 is methyl, ethyl or propyl, R 2 is hydrogen, methyl or ethyl, R 3 is hydrogen or methyl, R 4 is ##SPC23## R 5 is hydrogen, methyl or acetyl, or a non-toxic, pharmacologically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
19 words
A compound of claim 1, where R 5 is hydrogen, or a non-toxic, pharmacologically acceptable acid addition salt thereof.
Claim 4
Dependent Claim
17 words
A compound of claim 1, which is 5,9α-dimethyl-2-(3-methoxymethyl-furfuryl)-2'-hydroxy-6,7-benzomorphan or a non-toxic, pharmacologically acceptable acid addition salt thereof.
Claim 5
Dependent Claim
17 words
A compound of claim 1, which is (-)-5,9α-di-methyl-2-(3-methoxymethyl-furfuryl)-2'-hydroxy-6,7-benzomorphan or a non-toxic, pharmacologically acceptable acid addition salt thereof.
Claim 6
Dependent Claim
17 words
A compound of claim 1, which is 5,9α-dimethyl-2-[2-methoxymethyl-furyl-(3)-methyl]-2'-hydroxy-6,7-benzomorphan or a non-toxic, pharmacologically acceptable acid addition salt thereof.
Claim 7
Dependent Claim
17 words
A compound of claim 1, which is (-)-5,9α-dimethyl-2-[2-methoxymethyl-furyl-(3)-methyl]-2'-hydroxy-6,7-benzomorphan or a non-toxic, pharmacologically acceptable acid addition salt thereof.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-09-21 | 1980-03-22 | 1980-09-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-09-21 | 1984-03-22 | 1984-09-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-09-21 | 1988-03-22 | 1988-09-21 | $7700.00 | Window Closed / Lapsed |