Process for the preparation of heterocyclic compounds

Claim 1

Process for preparing compounds of the formula ##SPC9## by condensing an amine of the formula ##SPC10## with a carbonyl compound of the formula ##EQU7## in the presence of a hydrazine of the formula ##EQU8## wherein A is a benzene; naphthalene; pyridine; pyrimidine; or a pyrazine ring; or a benzene or naphthalene ring which is substituted with halogen, C 1 -C 4 -alkyl, cyclohexyl, phenyl, C 1 -C 4 -alkoxy, nitro, cyano, amino, C 1 -C 4 -alkyl-carbonylamino, C 1 -C 4 -alkyl-sulphonylamino, C 1 -C 4 -alkyl-sulphonyl, phenylsulphonyl, tolyl-sulphonyl, benzylsulphonyl, hydroxyl, carboxyl, carboalkoxy with 1 to 4 C atoms in the alkoxy group, carbonamide or sulphonamide; X is O, S or N-R 4 ; R 4 is hydrogen, C 1 -C 4 -alkyl; cyclohexyl; benzyl; phenethyl; phenyl or naphthyl; R 1 is hydrogen or C 1 -C 4 -alkyl; R 2 is hydrogen, C 1 -C 4 -alkyl; cyclohexyl; benzyl; phenethyl; phenyl; naphthyl; or pheyl substituted by C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, nitro, halogen, C 1 -C 4 -dialkylamino, or benzyl; R 3 is hydrogen, C 1 -C 4 -alkyl; cyclohexyl; benzyl; phenethyl; phenyl; naphthyl; phenyl substituted by C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, nitro, halogen, C 1 -C 4 -dialkylamino, or benzyl; benzthiazolyl-2; benzoxazolyl-2; benzimidazolyl-2; oxazolyl-2; triazolyl-2; thiazolyl-2; thiophenyl-2; purine-2; pyridine-2; pyrimidine-2; cinnolinyl-3; quinoxazinyl-2; or quinazolinyl-2; or R 2 and R 3 conjointly with the N atom form an indoline; carbazole or tetrahydroquinoline radical or one of the foregoing radicals substituted by C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy or halogen; R is hydrogen, C 1 -C 4 -alkyl; allyl; cyclohexyl; benzyl; phenethyl; phenyl or naphthyl; An - is an anion; X 1 is hydroxyl, methoxy, ethoxy or halogen; and X 2 and X 3 are halogen or conjointly are oxygen.