US3981864A
Expired / Lapsed
US
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1,3-Benzodioxol derivatives
Assignee: Eisai Co Ltd
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Filing: 1974-09-05
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Granted: 1976-09-21
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Expires: 1994-09-05
Abstract
Abstract 1,3-Benzodioxol derivatives, the new compounds, represented by the formula: ##SPC1## And the pharmacologically acceptable acid-addition salts thereof are provided, wherein R 1 and R 2 are lower alkyls or the both together may form a divalent alkylene, R 3 is a lower alkyl, phenyl, halogen-substituted phenyl or benzhydryl group, n is an integer of 2 or 3, and X stands for carbonyl (CO) or methylene (CH 2 ) bridge. The compounds in which X stands for the methylene exhibit durable anti-histamic activity with low toxicity, and are useful for therapeutic purposes, while the compounds in which X stands for the carbonyl bridge are easily convertible by reduction into the former compounds.
Inventors
- 👤 Satoru Tanaka
- 👤 Hideaki Watanabe
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 15:12
CPC Classifications
C; C07; C07D; C07D317/00; C07D317/08; C07D317/44; C07D317/46
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
47 words
A member of the group consisting of a compound of the formula ##SPC5## wherein m is an integer of 4 or 5, R 3 is methyl, phenyl, halogen substituted phenyl or benzhydryl, and n is an integer of 2 or 3 and a pharmalogically acceptable salt thereof.
Claim 2
Dependent Claim
47 words
A member of the group consisting of a compound of the formula ##SPC5## wherein m is an integer of 4 or 5, R 3 is methyl, phenyl, halogen substituted phenyl or benzhydryl, and n is an integer of 2 or 3 and a pharmalogically acceptable salt thereof.
Claim 3
Dependent Claim
19 words
A compound according to claim 1 wherein m is 5, R 3 is --CH 3 and n is 3.
References Cited (Backward Citations)
US3119826A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-09-21 | 1980-03-22 | 1980-09-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-09-21 | 1984-03-22 | 1984-09-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-09-21 | 1988-03-22 | 1988-09-21 | $7700.00 | Window Closed / Lapsed |