US3979447A
Expired / Lapsed
US
⏱️ 0.0 years remaining
γ-Glutamyl-4-nitroanilide compounds
Assignee: Roche Diagnostics GmbH
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Filing: 1973-11-27
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Granted: 1976-09-07
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Expires: 1993-11-27
Abstract
Abstract gamma -Glutamyl-4-nitroanilide compounds of the formula WHEREIN R is a gamma -glutamyl radical and X is an acid group, and salts of such compounds, are used to determine gamma -glutamyltranspeptidase by contacting a sample suspected of containing gamma -glutamyltranspeptidase with said compound and glycylglycine and determining the liberation of the resulting p-nitroaniline compound as a measure of the gamma -glutamyltranspeptidase activity initially present in the sample.
Inventors
- 👤 Erich Bernt
- 👤 Wolfgang Gruber
- 👤 Erich Haid
- 👤 Fritz Stahler
- 👤 August Wilhelm Wahlefeld
- 👤 Gunter Weimann
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 16:56
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/48
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
32 words
γ-Glutamyl-4-nitroanilide compound of the formula ##SPC3## wherein R is a γ-glutamyl radical and X is carboxyl or carboxyalhyl containing up to 6 carbon atoms; and alkali, alkaline earth, and ammonium salts thereof.
Claim 2
Dependent Claim
32 words
γ-Glutamyl-4-nitroanilide compound of the formula ##SPC3## wherein R is a γ-glutamyl radical and X is carboxyl or carboxyalhyl containing up to 6 carbon atoms; and alkali, alkaline earth, and ammonium salts thereof.
Claim 3
Dependent Claim
13 words
γ-Glutamyl-4-nitroanilide compound is claimed in claim 1, wherein X is a carboxyl group.
Claim 4
Dependent Claim
11 words
γ-Glutamyl-4-nitroanilide compound as claimed in claim 1, wherein X is carboxyalhyl.
Claim 5
Dependent Claim
11 words
γ-Glutamyl-4-nitroanilide compound as claimed in claim 1, wherein X is carboxymethyl.
Claim 6
Dependent Claim
12 words
γ-Glutamyl-4-nitroanilide compound as claimed in claim 1, in its ammonium salt form.
Claim 7
Dependent Claim
13 words
γ-Glutamyl-4-nitroanilide compound as claimed in claim 1, in its alkali metal salt form.
Claim 8
Dependent Claim
14 words
γ-Glutamyl-4-nitroanilide compound as claimed in claim 1, in its alkaline earth metal salt form.
Claim 9
Dependent Claim
12 words
γ-Glutamyl-4-nitroanilide compound as claimed in claim 1, in its sodium salt form.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-09-07 | 1980-03-08 | 1980-09-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-09-07 | 1984-03-08 | 1984-09-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-09-07 | 1988-03-08 | 1988-09-07 | $7700.00 | Window Closed / Lapsed |