US3968035A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Super-oxygenation method
Assignee: Eli Lilly and Co
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Filing: 1975-02-21
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Granted: 1976-07-06
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Expires: 1995-02-21
Abstract
Abstract Super-oxygenation of bio-oxidizable fluid in a bio-oxidation reactor is accomplished by continuously transferring a stream of said fluid from the top of the column of fluid in said reactor to an oxidator vessel equipped with a high-shear agitator, introducing an oxygen containing gas into the bottom of the column of fluid in said vessel, rapidly revolving said agitator concurrently with the flow of said gas into said vessel, and continuously transferring a stream of said fluid from the top of the column of fluid in said vessel to the bottom of the column of fluid in said reactor.
Inventors
- 👤 Robert H. L. Howe
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 18:50
CPC Classifications
C; C02; C02F; C02F3/00; C02F3/02; C02F3/12; C02F3/1278; C02F3/1284; C02F3/20; C02F3/205; C02F3/26; C12; C12M; C12M29/00; C12M29/02; C12M29/26; C12M41/00; C12M41/30; C12M41/34; Y; Y02; Y02W; Y02W10/00; Y02W10/10; Y10; Y10S; Y10S435/00; Y10S435/818
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
392 words
A method for continuously super-oxygenating a portion of the bio-oxidizable fluid from a bio-oxidation reactor to increase the concentration of oxygen dissolved in such fluid and reduce the energy required to effect the dissolution of such oxygen in such fluid comprising the steps of: a. continuously transferring a stream of said fluid in said reactor from a point near the top of the column of said fluid to a point near the bottom of an oxidator vessel equipped with a high shear agitator, said vessel having a capacity of from about one-tenth to one-two hundreth of the capacity of said reactor and having a diameter to height ratio of from about 1:2 to about 1:10 and said agitator having a diameter of from about 1:3 to 2:3 of the diameter of said vessel and impellers thereon having an effective surface area about the same as the cross-sectional area of said vessel, said reactor and said vessel being connected in a closed system; b. filling said vessel with a column of said fluid from said reactor to a point near the top of said vessel where there is disposed a return conduit from said vessel to a point near the bottom of said vessel to a point near the bottom of said reactor; c. introducing an oxygen containing gas into said fluid in said vessel at a point near the bottom of said vessel, at a pressure of from about 1.0 to about 40 psig; d. revolving said agitator in said fluid in said vessel while said gas is being introduced thereinto; e. operating said agitator at from about 150 to about 1,800 rpm wherein the energy utilization is from about 5 to about 15 horsepower per 1,000 gallons of said fluid in said vessel; f. shearing said oxygen containing gas into submillimeter bubbles of the order of from about 10.sup. -1 to about 10.sup. -4 centimeters in said fluid; and g. continuously transferring a stream of the bio-oxidizable fluid containing the sub-millimeter bubbles of oxygen containing gas from said vessel to a point near the bottom of said reactor, said stream being taken from a point near the top of said column of said fluid in said vessel, said transferring being conducted at a rate such that the volume of said fluid in said vessel is renewed every 30 to 240 seconds.
Claim 2
Independent Claim
392 words
A method for continuously super-oxygenating a portion of the bio-oxidizable fluid from a bio-oxidation reactor to increase the concentration of oxygen dissolved in such fluid and reduce the energy required to effect the dissolution of such oxygen in such fluid comprising the steps of: a. continuously transferring a stream of said fluid in said reactor from a point near the top of the column of said fluid to a point near the bottom of an oxidator vessel equipped with a high shear agitator, said vessel having a capacity of from about one-tenth to one-two hundreth of the capacity of said reactor and having a diameter to height ratio of from about 1:2 to about 1:10 and said agitator having a diameter of from about 1:3 to 2:3 of the diameter of said vessel and impellers thereon having an effective surface area about the same as the cross-sectional area of said vessel, said reactor and said vessel being connected in a closed system; b. filling said vessel with a column of said fluid from said reactor to a point near the top of said vessel where there is disposed a return conduit from said vessel to a point near the bottom of said vessel to a point near the bottom of said reactor; c. introducing an oxygen containing gas into said fluid in said vessel at a point near the bottom of said vessel, at a pressure of from about 1.0 to about 40 psig; d. revolving said agitator in said fluid in said vessel while said gas is being introduced thereinto; e. operating said agitator at from about 150 to about 1,800 rpm wherein the energy utilization is from about 5 to about 15 horsepower per 1,000 gallons of said fluid in said vessel; f. shearing said oxygen containing gas into submillimeter bubbles of the order of from about 10.sup. -1 to about 10.sup. -4 centimeters in said fluid; and g. continuously transferring a stream of the bio-oxidizable fluid containing the sub-millimeter bubbles of oxygen containing gas from said vessel to a point near the bottom of said reactor, said stream being taken from a point near the top of said column of said fluid in said vessel, said transferring being conducted at a rate such that the volume of said fluid in said vessel is renewed every 30 to 240 seconds.
Claim 3
Dependent Claim
24 words
The method according to claim 1 wherein a pump is utilized to continuously transfer said fluid from said reactor to said vessel and return.
Claim 4
Dependent Claim
24 words
The method according to claim 1 wherein the ratio of the diameter of said agitator to the diameter of said vessel is about 1:2.
Claim 5
Dependent Claim
20 words
The method according to claim 1 wherein said oxygen containing gas is substantially pure O 2 from vaporized liquid oxygen.
Claim 6
Dependent Claim
14 words
The method according to claim 1 wherein said oxygen containing gas is compressed air.
Claim 7
Dependent Claim
31 words
The method according to claim 1 wherein the transfer rate of said fluid is such that the volume of said fluid in said vessel is renewed every 90 to 120 seconds.
Claim 8
Dependent Claim
20 words
The method of super-oxygenating the growth medium of an antibiotic fermentation process comprising super-oxygenating such medium according to claim 1.
Claim 9
Dependent Claim
18 words
The method of super-oxygenating a food fermentation process requiring oxygenation comprising super-oxygenating said process according to claim 1.
Claim 10
Dependent Claim
18 words
The method of super-oxygenating a beverage fermentation process requiring oxygenation comprising super-oxygenating said process according to claim 1.
Claim 11
Dependent Claim
20 words
The method of super-oxygenating the bio-degradable matter in a waste treatment process comprising super-oxygenating said process according to claim 1.
Claim 12
Dependent Claim
18 words
The method of claim 10 wherein said bio-degradable matter is comprised of waste from an antibiotic fermentation process.
Claim 13
Dependent Claim
20 words
The method of claim 10 wherein said bio-degradable matter is comprised of liquid organic waste entering a sewage disposal process.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-07-06 | 1980-01-05 | 1980-07-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-07-06 | 1984-01-05 | 1984-07-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-07-06 | 1988-01-05 | 1988-07-06 | $7700.00 | Window Closed / Lapsed |