US3966899A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of treatment of medicines
Assignee: Individual
•
Filing: 1975-03-12
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Granted: 1976-06-29
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Expires: 1995-03-12
Abstract
Abstract A method of manufacturing a pharmaceutical having a plurality of active ingredients so that each active ingredient will be released at substantially the same uniform rate involves mixing the active ingredients with beta-1, 4-glucan and pulverizing the mixture.
Inventors
- 👤 Yoshinobu Nakai
- 👤 Keiji Yamamoto
- 👤 Masahiro Nakano
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 15:10
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/14; A61K9/141; A61K9/146; A61K9/20; A61K9/2004; A61K9/2022; A61K9/205
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
51 words
The method of manufacturing a pharmaceutical comprising a plurality of pharmacologically active ingredients whereby upon administration to a patient each active ingredient will be released therefrom at substantially the same uniform rate, said method consisting essentially of mixing a plurality of pharmacologically active ingredients with beta-1, 4-glucan, and pulverizing the mixture.
Claim 2
Independent Claim
51 words
The method of manufacturing a pharmaceutical comprising a plurality of pharmacologically active ingredients whereby upon administration to a patient each active ingredient will be released therefrom at substantially the same uniform rate, said method consisting essentially of mixing a plurality of pharmacologically active ingredients with beta-1, 4-glucan, and pulverizing the mixture.
Claim 3
Dependent Claim
16 words
The method of claim 1 wherein at least one of the active ingredients is sparingly soluble.
Claim 4
Dependent Claim
15 words
The method of claim 1 wherein at least one of the active ingredients is water-soluble.
Claim 5
Dependent Claim
28 words
The method of claim 1 wherein pulverization is carried to the extent that diffraction peak characteristics of any crystalline substance ceases to be detectable by X-ray diffraction techniques.
Claim 6
Dependent Claim
20 words
The method of claim 1 including the additional step of incorporating the pulverized mixture into a solid pharmaceutical dosage form.
Claim 7
Dependent Claim
17 words
The method of claim 1 including the additional step of compacting the pulverized mixture into a tablet.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-06-29 | 1979-12-29 | 1980-06-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-06-29 | 1983-12-29 | 1984-06-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-06-29 | 1987-12-29 | 1988-06-29 | $7700.00 | Window Closed / Lapsed |