US3966709A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Penicillins and cephalosporins and their production
Assignee: Bayer AG
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Filing: 1974-10-25
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Granted: 1976-06-29
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Expires: 1994-10-25
Abstract
Abstract beta -Lactams of the formula AND PHARMACEUTICALLY ACCEPTABLE NONTOXIC SALTS THEREOF WHEREIN A is hydrogen or alkyl of 1 to 4 carbon atoms; B is phenyl, methylphenyl, chlorophenyl, hydroxyphenyl or cyclohexa-1,4-dien-1-yl; R is a moiety of the formula WHEREIN E is hydrogen -OH or -O- CO-CH3; and C constitutes a center of chirality; are produced which exhibit antibiotic activity.
Inventors
- 👤 Hans-Bodo Konig
- 👤 Karl Georg Metzger
- 👤 Wilfried Schrock
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 22:17
CPC Classifications
C; C07; C07D; C07D499/00
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
53 words
A compound selected from the group consisting of a penicillin of the formula: ##SPC20## and the pharmaceutically acceptable acid addition salts thereof wherein the carbon atom designated C constitutes a center of chirality; A is hydrogen or alkyl of 1 to 4 carbon atoms; and B is phenyl, methylphenyl, chlorophenyl, hydroxyphenyl or cyclohexa-1,4-dien-1-yl.
Claim 2
Dependent Claim
53 words
A compound selected from the group consisting of a penicillin of the formula: ##SPC20## and the pharmaceutically acceptable acid addition salts thereof wherein the carbon atom designated C constitutes a center of chirality; A is hydrogen or alkyl of 1 to 4 carbon atoms; and B is phenyl, methylphenyl, chlorophenyl, hydroxyphenyl or cyclohexa-1,4-dien-1-yl.
Claim 3
Dependent Claim
15 words
A compound according to claim 1 wherein B is phenyl, 4-methylphenyl, 4-chlorophenyl, 4-hydroxyphenyl, or cyclohexa-1,4-dien-1-yl.
Claim 4
Dependent Claim
13 words
A compound according to claim 2 wherein A is hydrogen, methyl or ethyl.
Claim 5
Dependent Claim
13 words
A compound according to claim 3 wherein A is hydrogen or methyl; and
Claim 6
Dependent Claim
13 words
A compound according to claim 6 wherein B is phenyl, p-hydroxyphenyl or cyclohexa-1,4-dien-1-yl.
Claim 7
Dependent Claim
10 words
A compound according to claim 4 wherein A is hydrogen.
Claim 8
Dependent Claim
11 words
A compound according to claim 1 wherein said penicillin is α-(2-oxoimidazolidin-1-ylthiocarbonylamino)benzly-penicillin.
Claim 9
Dependent Claim
10 words
The sodium salt of the penicillin according to claim 7.
Claim 10
Dependent Claim
11 words
A compound according to claim 1 wherein said penicillin is α-(2-oxoimidazolidin-1-ylthiocarbonylamino)-4-hydroxybenzylpenicillin.
Claim 11
Dependent Claim
10 words
The sodium salt of the penicillin according to claim 9.
Claim 12
Dependent Claim
11 words
A compound according to claim 1 wherein said penicillin is α(2-oxoimidazolidin-1-ylthiocarbonylamino)-2,5-dihydrobenzylpenicillin.
Claim 13
Dependent Claim
10 words
The sodium salt of the penicilllin according to claim 11.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-06-29 | 1979-12-29 | 1980-06-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-06-29 | 1983-12-29 | 1984-06-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-06-29 | 1987-12-29 | 1988-06-29 | $7700.00 | Window Closed / Lapsed |