US3963725A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof
Assignee: Astellas Pharma Inc
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Filing: 1974-07-19
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Granted: 1976-06-15
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Expires: 1994-07-19
Abstract
Abstract The present invention relates to new 1,2,3,4-tetrahydroisoquinoline derivatives, which have relaxing activity on smooth muscles. The present invention also relates to the preparation of new and known 1,2,3,4-tetraydroisoquinoline derivatives.
Inventors
- 👤 Teiji Kishimoto
- 👤 Yoshiyuki Kaneda
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 20:58
CPC Classifications
C; C07; C07D; C07D217/00; C07D217/12; C07D217/14; C07D217/16
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
27 words
A 1,2,3,4-tetrahydroisoquinoline having the formula: ##SPC8## wherein R is phenyl having a lower alkylthio substituent, and pharmaceutically acceptable salts thereof, wherein "lower" refers to 1-6 carbon atom(s).
Claim 2
Dependent Claim
27 words
A 1,2,3,4-tetrahydroisoquinoline having the formula: ##SPC8## wherein R is phenyl having a lower alkylthio substituent, and pharmaceutically acceptable salts thereof, wherein "lower" refers to 1-6 carbon atom(s).
Claim 3
Dependent Claim
13 words
The compounds of claim 1, wherein R is phenyl having a methylthio substituent.
Claim 4
Dependent Claim
12 words
The compound of claim 2, wherein R is 4-methylthiophenyl and its hydrochloride.
References Cited (Backward Citations)
US3378561A
Cited
US3497516A
Cited
US3437662A
Cited
US3452086A
Cited
US3389141A
Cited
US3846432A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-06-15 | 1979-12-15 | 1980-06-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-06-15 | 1983-12-15 | 1984-06-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-06-15 | 1987-12-15 | 1988-06-15 | $7700.00 | Window Closed / Lapsed |