US3962249A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1-(3-phenylpropyl)-4-furoylpiperazine derivatives
Assignee: Kyorin Pharmaceutical Co Ltd
•
Filing: 1975-03-06
•
Granted: 1976-06-08
•
Expires: 1995-03-06
Abstract
Abstract 1-(3-Phenylpropyl)-4-furoylpiperazine represented by the following general formula (I), ##SPC1## (wherein: R 1 and R.sub. 2, which may be the same or different, each represents a hydrogen atom or a lower alkyl group containing 1 to 4 carbon atoms; R 3 represents a hydrogen atom, a halogen atom, a lower alkyl group containing 1 to 4 carbon atoms, or a lower alkoxy groups containing 1 to 4 carbon atoms; R 4 and R 5 , which may be the same or different, each represents a hydrogen atom or a lower alkyl group containing 1 to 4 carbon atoms), and pharmaceutically acceptable addition salts thereof.
Inventors
- 👤 Tsutomu Irikura
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 11:55
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/02; C07D307/34; C07D307/38; C07D307/40; C07D307/46; C07D307/48; C07D405/00; C07D405/02; C07D405/06
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
73 words
A compound of formula ##SPC4## wherein R 1 and R 2 , independently of each other, represent hydrogen or alkyl having 1 to 4 carbon atoms; R 3 represents hydrogen, halogen, alkyl having 1 to 4 carbon atoms, or alkoxy having 1 to 4 carbon atoms; R 4 and R 5 independently of each other, represent hydrogen or alkyl having 1 to 4 carbon atoms, or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
73 words
A compound of formula ##SPC4## wherein R 1 and R 2 , independently of each other, represent hydrogen or alkyl having 1 to 4 carbon atoms; R 3 represents hydrogen, halogen, alkyl having 1 to 4 carbon atoms, or alkoxy having 1 to 4 carbon atoms; R 4 and R 5 independently of each other, represent hydrogen or alkyl having 1 to 4 carbon atoms, or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
9 words
The compound according to claim 1, namely 1-(3-Phenylpropyl)-4-(2-furoyl)piperazine hydrochloride.
Claim 4
Dependent Claim
9 words
The compound according to claim 1, namely trans-1-(3-Phenylpropyl)-2,5-dimethyl-4-(2-furoyl)piperazine hydrochloride.
Claim 5
Dependent Claim
9 words
The compound according to claim 1, namely 1-(3-Phenylpropyl)-2-methyl-4-(2-furoyl)piperazine hydrochloride.
Claim 6
Dependent Claim
9 words
The compound according to claim 1, namely 1-(3-Phenylpropyl)-3-methyl-4-(2-furoyl)piperazine hydrochloride.
Claim 7
Dependent Claim
9 words
The compound according to claim 1, namely 1-(3-Phenylpropyl)-3,3-dimethyl-4-(2-furoyl)piperazine hydrochloride.
Claim 8
Dependent Claim
9 words
The compound according to claim 1, namely 1-[3-(p-Methoxyphenyl)propyl]-4-(2-furoyl)piperazine hydrochloride.
Claim 9
Dependent Claim
9 words
The compound according to claim 1, namely 1-[3-(o-Methylphenyl)propyl]-4-(2-furoyl)piperazine hydrochloride.
Claim 10
Dependent Claim
9 words
The compound according to claim 1, namely 1-[3-(m-Methylphenyl)propyl]-4-(2-furoyl)piperazine hydrochloride.
Claim 11
Dependent Claim
9 words
The compound according to claim 1, namely 1-[3-(p-Ethoxyphenyl)propyl]-4-(2-furoyl)piperazine hydrochloride.
Claim 12
Dependent Claim
9 words
The compound according to claim 1, namely 1-(3-Phenylpropyl)-4-(5-methyl-2-furoyl)piperazine hydrochloride.
Claim 13
Dependent Claim
9 words
The compound according to claim 1, namely 1-(3-Phenylpropyl)-4-(2-methyl-3-furoyl)piperazine hydrochloride.
Claim 14
Dependent Claim
9 words
The compound according to claim 1, namely 1-(3-Phenylpropyl)-4-(5-methyl-3-furoyl)piperazine hydrochloride.
Claim 15
Dependent Claim
9 words
The compound according to claim 1, namely 1-(3-Phenylpropyl)-4-(2,5-dimethyl-3-furoyl)piperazine hydrochloride.
Claim 16
Dependent Claim
9 words
The compound according to claim 1, namely cis-1-(3-Phenylpropyl)-2,3-dimethyl-4-(2-furoyl)piperazine hydrochloride.
Claim 17
Dependent Claim
9 words
The compound according to claim 1, namely trans-1-[3-(o-Methylphenyl)propyl]-2,5-dimethyl-4-(2-furoyl)piperazine hydrochloride.
Claim 18
Dependent Claim
9 words
The compound according to claim 1, namely trans-1-[3-(m-Methylphenyl)propyl]-2,5-dimethyl-4-(2-furoyl)piperazine hydrochloride.
Claim 19
Dependent Claim
9 words
The compound according to claim 1, namely trans-1-(3-Phenylpropyl)-2,3-dimethyl-4-(2-furoyl)piperazine hydrochloride.
Claim 20
Dependent Claim
9 words
The compound according to claim 1, namely trans-1-[3-(o-Methoxyphenyl)propyl]-2,5-dimethyl-4-(2-furoyl)piperazine hydrochloride.
Claim 21
Dependent Claim
9 words
The compound according to claim 1, namely 1-[3-(o-Methylphenyl)propyl]-3-methyl-4-(2-furoyl)piperazine hydrochloride.
Claim 22
Dependent Claim
9 words
The compound according to claim 1, namely trans-1-(3-Phenylpropyl)-2,5-dimethyl-4-(5-methyl-3-furoyl)piperazine hydrochloride.
Claim 23
Dependent Claim
9 words
The compound according to claim 1, namely trans-1-[3-(o-Methylphenyl)propyl]-2,5-dimethyl-4-(5-methyl-3-furoyl)piperazine hydrochloride.
Claim 24
Dependent Claim
9 words
The compound according to claim 1, namely trans-1-(3-Phenylpropyl)-2,5-dimethyl-4-(3-methyl-2-furoyl)piperazine hydrochloride.
Claim 25
Dependent Claim
9 words
The compound according to claim 1, namely trans-1-(3-Phenylpropyl)-2,5-dimethyl-4-(5-methyl-2-furoyl)piperazine hydrochloride.
Claim 26
Dependent Claim
9 words
The compound according to claim 1, namely trans-1-(3-Phenylpropyl)-2,5-dimethyl-4-(2-methyl-3-furoyl)piperazine hydrochloride.
Claim 27
Dependent Claim
9 words
The compound according to claim 1, namely 1-(3-Phenylpropyl)-3-methyl-4-(5-methyl-2-furoyl)piperazine hydrochloride.
Claim 28
Dependent Claim
9 words
The compound according to claim 1, namely 1-(3-Phenylpropyl)-3-methyl-4-(3-methyl-2-furoyl)piperazine hydrochloride.
Claim 29
Dependent Claim
9 words
The compound according to claim 1, namely 1-[3-(o-Methylphenyl)propyl]-3-methyl-4-(3-methyl-2-furoyl)piperazine hydrochloride.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-06-08 | 1979-12-08 | 1980-06-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-06-08 | 1983-12-08 | 1984-06-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-06-08 | 1987-12-08 | 1988-06-08 | $7700.00 | Window Closed / Lapsed |