US3962224A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cephalosporin compounds
Assignee: Merck and Co Inc
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Filing: 1973-03-05
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Granted: 1976-06-08
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Expires: 1993-03-05
Abstract
Abstract Novel 7-azido-3-cephem compounds are prepared via α-amino-phosphonoacetate esters. The cephem compounds are intermediates for the preparation of novel and known useful antibiotic cephalosporins.
Inventors
- 👤 Burton G. Christensen
- 👤 Ronald W. Ratcliffe
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-10 01:27
CPC Classifications
C; C07; C07F; C07F9/00; C07F9/02; C07F9/547; C07F9/553; C07F9/568
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
54 words
A dl-7α-azido compound of the formula: ##SPC17## wherein R 1 is a blocking group and R' is pyrrolidinylcarbonyloxy, carbamoyloxy, N-substituted carbamoyloxy, or N,N-disubstituted carbamoyloxy wherein the carbamoyl substituents may be the same or different and are lower alkyl, halogented lower alkyl, lower alkoxy, chloro, bromo, fluoro, benzyl, p-methoxy benzyl, phenethyl, p-methoxy phenethyl, or p-aminophenethyl.
Claim 2
Dependent Claim
54 words
A dl-7α-azido compound of the formula: ##SPC17## wherein R 1 is a blocking group and R' is pyrrolidinylcarbonyloxy, carbamoyloxy, N-substituted carbamoyloxy, or N,N-disubstituted carbamoyloxy wherein the carbamoyl substituents may be the same or different and are lower alkyl, halogented lower alkyl, lower alkoxy, chloro, bromo, fluoro, benzyl, p-methoxy benzyl, phenethyl, p-methoxy phenethyl, or p-aminophenethyl.
Claim 3
Dependent Claim
21 words
The compound of claim 1 wherein R 1 is methyl, tertiary butyl, phenacyl, p-bromophenacyl, 2,2,2-trichloroethyl, p-methoxybenzyl, p-nitrobenzyl, benzhydryl, p-methoxyphenoxymethyl or methoxymethyl.
Claim 4
Dependent Claim
9 words
The compound of claim 1 wherein R' is carbamoyloxy.
Claim 5
Dependent Claim
9 words
The compound of claim 1 wherein R' is (N,N-di-p-methoxybenzyl)carbamoyloxy.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-06-08 | 1979-12-08 | 1980-06-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-06-08 | 1983-12-08 | 1984-06-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-06-08 | 1987-12-08 | 1988-06-08 | $7700.00 | Window Closed / Lapsed |