US3960905A
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Diacylglycerophosphoric acid esters of aminoethanol and methylaminoethanol and method of preparing the same
Assignee: Max-Planck-Gesellschaft zur Förderung der Wissenschaften eV
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Filing: 1974-08-28
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Granted: 1976-06-01
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Expires: 1994-08-28
Abstract
Abstract Aminoethyl and methylaminoethyl esters of diacylglycerophosphoric acid in ich the acyl groups are alkanoyl or alkenoyl having 10 to 22 carbon atoms are prepared in good yield by reaction of the corresponding β-bromoethyl esters with ammonia or methylamine base.
Inventors
- 👤 Hansjorg Eibl
- 👤 Alfar Nicksch
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 22:20
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/66; A61K31/683; A61K31/685; C; C07; C07F; C07F9/00; C07F9/02; C07F9/06; C07F9/08; C07F9/09; C07F9/10
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
66 words
A method of preparing a diacyl-glycerophosphoric acid ester of β-amino-ethanol or N-methyl-β-amino-ethanol which comprises reacting a diacyl-glycerophosphoric acid ester of β-bromoethanol with a base of the formula NH 2 R in a liquid solvent medium until said ester of β-amino-ethanol or N-methyl-β-amino-ethanol is formed, in said formula R being hydrogen or methyl, acyl in said diacyl being alkanoyl or alkenoyl having 10 to 22 carbon atoms.
Claim 2
Independent Claim
66 words
A method of preparing a diacyl-glycerophosphoric acid ester of β-amino-ethanol or N-methyl-β-amino-ethanol which comprises reacting a diacyl-glycerophosphoric acid ester of β-bromoethanol with a base of the formula NH 2 R in a liquid solvent medium until said ester of β-amino-ethanol or N-methyl-β-amino-ethanol is formed, in said formula R being hydrogen or methyl, acyl in said diacyl being alkanoyl or alkenoyl having 10 to 22 carbon atoms.
Claim 3
Dependent Claim
32 words
A method as set forth in claim 1, wherein aid solvent medium essentially consists of chloroform and at least one member of the group consisting of acetonitrile, nitromethane, methanol, ethanol, and water.
Claim 4
Dependent Claim
21 words
A method as set forth in claim 2, wherein said ester of β-bromoethanol is reacted with an excess of said base.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-06-01 | 1979-12-01 | 1980-06-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-06-01 | 1983-12-01 | 1984-06-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-06-01 | 1987-12-01 | 1988-06-01 | $7700.00 | Window Closed / Lapsed |