US3959476A
Expired / Lapsed
US
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Antihypertensive substituted triazoles
Assignee: Astra Lakemedel AB
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Filing: 1974-06-11
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Granted: 1976-05-25
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Expires: 1994-06-11
Abstract
Abstract Compounds having the general formula METHODS FOR THE PREPARATION THEREOF AND USE IN THE TREATMENT OF HYPERTENSION.
Inventors
- 👤 Hans Erik Eriksson
- 👤 Gosta Lennart Florvall
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 04:58
CPC Classifications
C; C07; C07D; C07D249/00; C07D249/02; C07D249/08; C07D249/10; C07D249/14
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
86 words
A compound of the formula ##SPC9## or a pharmaceutically acceptable salt thereof in which formula R 1 , R 2 and R 3 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R 4 represents a hydrogen atom or a lower alkyl group and R 5 represents a hydrogen atom or a lower alkyl group, provided that R 4 is a lower alkyl group when R 1 , R 2 and R 3 are all hydrogen.
Claim 2
Dependent Claim
86 words
A compound of the formula ##SPC9## or a pharmaceutically acceptable salt thereof in which formula R 1 , R 2 and R 3 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R 4 represents a hydrogen atom or a lower alkyl group and R 5 represents a hydrogen atom or a lower alkyl group, provided that R 4 is a lower alkyl group when R 1 , R 2 and R 3 are all hydrogen.
Claim 3
Dependent Claim
75 words
A compound according to claim 1 characterized by the formula I, or a pharmaceutically acceptable salt thereof, in which formula R 1 , R 2 and R 3 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R 4 represents a hydrogen atom and R 5 represents a hydrogen atom, provided that R 1 , R 2 and R 3 are not all simultaneously hydrogen.
Claim 4
Dependent Claim
17 words
A compound according to claim 1 characterized by the formula ##SPC10## or a pharmaceutically acceptable salt thereof.
Claim 5
Dependent Claim
112 words
An antihypertensive pharmaceutical preparation which comprises as active ingredient from 0.1% to 95% by weight of said preparation of a compound of the formula ##SPC11## or a pharmaceutically acceptable salt thereof in which formula R 1 , R 2 and R 3 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R 4 represents a hydrogen atom or a lower alkyl group and R 5 represents a hydrogen atom or a lower alkyl group, provided that R 4 is a lower alkyl group when R 1 , R 2 and R 3 are all hydrogen, in association with a pharmaceutically acceptable carrier.
Claim 6
Dependent Claim
112 words
An antihypertensive pharmaceutical preparation which comprises as active ingredient from 0.1% to 95% by weight of said preparation of a compound of the formula ##SPC11## or a pharmaceutically acceptable salt thereof in which formula R 1 , R 2 and R 3 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R 4 represents a hydrogen atom or a lower alkyl group and R 5 represents a hydrogen atom or a lower alkyl group, provided that R 4 is a lower alkyl group when R 1 , R 2 and R 3 are all hydrogen, in association with a pharmaceutically acceptable carrier.
Claim 7
Dependent Claim
64 words
An antihypertensive pharmaceutical preparation according to claim 4 wherein R 1 , R 2 and R 3 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R 4 represents a hydrogen atom and R 5 represents a hydrogen atom, provided that R 1 , R 2 and R 3 are not all simultaneously hydrogen.
Claim 8
Independent Claim
117 words
A method for the treatment of hypertension, which comprises administration to a host suffering from such ailment an antihypertensive pharmaceutical preparation which comprises, as active ingredient, a therapeutically acceptable amount of a compound of the formula ##SPC12## or a pharmaceutically acceptable salt thereof in which formula R 1 , R 2 and R 3 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R 4 represents a hydrogen atom or a lower alkyl group and R 5 represents a hydrogen atom or a lower alkyl group, provided that R 4 is a lower alkyl group when R 1 , R 2 and R 3 are all hydrogen.
Claim 9
Independent Claim
117 words
A method for the treatment of hypertension, which comprises administration to a host suffering from such ailment an antihypertensive pharmaceutical preparation which comprises, as active ingredient, a therapeutically acceptable amount of a compound of the formula ##SPC12## or a pharmaceutically acceptable salt thereof in which formula R 1 , R 2 and R 3 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R 4 represents a hydrogen atom or a lower alkyl group and R 5 represents a hydrogen atom or a lower alkyl group, provided that R 4 is a lower alkyl group when R 1 , R 2 and R 3 are all hydrogen.
Claim 10
Dependent Claim
62 words
A method according to claim 6, wherein R 1 , R 2 and R 3 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R 4 represents a hydrogen atom and R 5 represents a hydrogen atom, provided that R 1 , R 2 and R 3 are not all simultaneously hydrogen.
References Cited (Backward Citations)
US3516995A
Cited
US3775405A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-05-25 | 1979-11-24 | 1980-05-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-05-25 | 1983-11-24 | 1984-05-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-05-25 | 1987-11-24 | 1988-05-25 | $7700.00 | Window Closed / Lapsed |