US3957995A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical composition comprising vincamine and theophylline
Assignee: Parcor SARL
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Filing: 1974-12-23
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Granted: 1976-05-18
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Expires: 1994-12-23
Abstract
Abstract The herein disclosed invention is directed to pharmaceutical compositions of vincamine and theophylline having cerebral vasodilator activity.
Inventors
- 👤 Armand Amselem
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 16:14
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495; A61K31/505; A61K31/519; A61K31/52
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
29 words
A pharmaceutical composition comprising 0.005 to 0.50 grams of vincamine and 0.050 to 0.500 grams of theophylline, the weight ratio of vincamine to theophylline being from 0.01 to 0.1:1.
Claim 2
Dependent Claim
29 words
A pharmaceutical composition comprising 0.005 to 0.50 grams of vincamine and 0.050 to 0.500 grams of theophylline, the weight ratio of vincamine to theophylline being from 0.01 to 0.1:1.
Claim 3
Dependent Claim
15 words
Composition as claimed in claim 1, wherein said weight ratio is from 0.025 to 0.075:1.
Claim 4
Dependent Claim
32 words
Composition as claimed in claim 1, wherein vincamine is present as a derivative thereof selected from the group consisting of a non-toxic addition salt thereof and a non-toxic quaternary ammonium derivative thereof.
Claim 5
Dependent Claim
28 words
Composition as claimed in claim 1, wherein theophylline is present as a derivative thereof selected from the group consisting of theophylline ethylenediamine, dihydroxypropyl theophylline and diethylene-diamine theophylline ethanoate.
Claim 6
Dependent Claim
32 words
Composition as claimed in claim 2, wherein vincamine is present as a derivative thereof selected from the group consisting of a non-toxic addition salt thereof and a non-toxic quaternary ammonium derivative thereof.
Claim 7
Dependent Claim
25 words
Composition as claimed in claim 3, wherein theophylline is present as a derivative thereof selected from the group consisting of theophylline and diethylene-diamine theophylline ethanoate.
Claim 8
Dependent Claim
25 words
Composition as claimed in claim 1, which comprises 0.010 to 0.100 grams of phenobarbital, the weight ratio of phenobarbital to theophylline being 2 to 0.02:1.
Claim 9
Dependent Claim
17 words
Composition as claimed in claim 7, wherein said weight ratio of the phenobarbital to theophylline is 0.1:1.
Claim 10
Dependent Claim
11 words
Composition as claimed in claim 1 in the form of tablets.
Claim 11
Dependent Claim
11 words
Composition as claimed in claim 1 in the form of capsules.
Claim 12
Dependent Claim
11 words
Composition as claimed in claim 1 in the form of suppository.
Claim 13
Dependent Claim
45 words
A process for treating a patient who suffers from cerebral circulatory deficiency, which comprises administering daily to said patient from 0.005 to 0.100 g vincamine together with from 0.05 to 1.50 g theophylline, the weight ratio of vincamine to theophylline being from 0.01 to 0.1:1.
Claim 14
Dependent Claim
45 words
A process for treating a patient who suffers from cerebral circulatory deficiency, which comprises administering daily to said patient from 0.005 to 0.100 g vincamine together with from 0.05 to 1.50 g theophylline, the weight ratio of vincamine to theophylline being from 0.01 to 0.1:1.
Claim 15
Dependent Claim
37 words
A process as claimed in claim 12, which comprises administering daily to said patient from 0.010 to 0.300 g phenobarbital together with said vincamine and theophylline, the weight ratio of phenobarbital to theophylline being 2 to 0.02:1.
Claim 16
Dependent Claim
40 words
Process as claimed in claim 13, which comprises administering said vincamine, theophylline and phenobarbital as dosage unit forms, each form comprising from 0.005 to 0.050 g vincamine, from 0.050 to 0.500 g theophylline and from 0.010 to 0.100 g phenobarbital.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-05-18 | 1979-11-17 | 1980-05-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-05-18 | 1983-11-17 | 1984-05-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-05-18 | 1987-11-17 | 1988-05-18 | $7700.00 | Window Closed / Lapsed |