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US3957994A Expired / Lapsed US ⏱️ 0.0 years remaining

Topical anti-inflammatory composition and method of use

Assignee: Whitby Research Inc
•
Filing: 1974-12-19
•
Granted: 1976-05-18
•
Expires: 1994-12-19
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Abstract

Abstract There is disclosed a novel topical anti-inflammatory composition comprising theophylline and 2-pyrrolidone or an N-lower alkyl-2-pyrrolidone.

Inventors

  • 👤 Richard Allen Schroer

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 07:02
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495; A61K31/505; A61K31/519; A61K31/52; A61K47/00; A61K47/06; A61K47/22; A61K9/00; A61K9/0012; A61K9/0014

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 37 words
A composition useful in the treatment of inflammation of the skin comprising about 0.1 to about 1 percent by weight of theophylline together with about 5 to about 99.9 percent by weight of 2-pyrrolidone or N-lower alkyl-2-pyrrolidone.
Claim 2
Dependent Claim 37 words
A composition useful in the treatment of inflammation of the skin comprising about 0.1 to about 1 percent by weight of theophylline together with about 5 to about 99.9 percent by weight of 2-pyrrolidone or N-lower alkyl-2-pyrrolidone.
Claim 3
Dependent Claim 14 words
The composition of claim 1 wherein the N-lower alkyl substituent has 1-4 carbon atoms.
Claim 4
Dependent Claim 11 words
A composition of claim 1 wherein the N-lower alkyl-2-pyrrolidone is N-methyl-2-pyrrolidone.
Claim 5
Dependent Claim 29 words
A composition useful in the treatment of inflammation of the skin comprising about 0.3 theophylline and a topical carrier containing about 10 to about 50 percent by weight N-methyl-2-pyrrolidone.
Claim 6
Dependent Claim 29 words
A composition useful in the treatment of inflammation of the skin comprising about 0.3 theophylline and a topical carrier containing about 10 to about 50 percent by weight N-methyl-2-pyrrolidone.
Claim 7
Independent Claim 57 words
A method for temporarily alleviating the symptoms of inflammation of the skin in humans and animals comprising topically administering to a human or animal an effective amount of a composition containing about 0.1 to about 1 percent by weight of theophylline together with about 5 to about 99.9 percent by weight of 2-pyrrolidone or an N-lower alkyl-2-pyrrolidone.
Claim 8
Independent Claim 57 words
A method for temporarily alleviating the symptoms of inflammation of the skin in humans and animals comprising topically administering to a human or animal an effective amount of a composition containing about 0.1 to about 1 percent by weight of theophylline together with about 5 to about 99.9 percent by weight of 2-pyrrolidone or an N-lower alkyl-2-pyrrolidone.
Claim 9
Dependent Claim 15 words
The method of claim 5 wherein the N-lower alkyl substituent has 1- 4 carbon atoms.
Claim 10
Dependent Claim 11 words
The method of claim 5 wherein the N-lower alkyl-2-pyrrolidone is N-methyl-2-pyrrolidone.
Claim 11
Independent Claim 53 words
A method for temporarily alleviating the symptoms of inflammation of the skin in humans and animals comprising topically administering to a human or animal an effective amount of a composition containing about 0.3 percent by weight of theophylline and a topical carrier containing about 10 to about 50 percent by weight of N-methyl-2-pyrrolidone.
Claim 12
Independent Claim 53 words
A method for temporarily alleviating the symptoms of inflammation of the skin in humans and animals comprising topically administering to a human or animal an effective amount of a composition containing about 0.3 percent by weight of theophylline and a topical carrier containing about 10 to about 50 percent by weight of N-methyl-2-pyrrolidone.
Claim 13
Dependent Claim 10 words
The method of claim 5 wherein the inflammation is sunburn.
Claim 14
Dependent Claim 10 words
The method of claim 8 wherein the inflammation is sunburn.

References Cited (Backward Citations)

US3457263A Cited
US3472931A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-05-18 1979-11-17 1980-05-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-05-18 1983-11-17 1984-05-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-05-18 1987-11-17 1988-05-18 $7700.00 Window Closed / Lapsed

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