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US3950427A Expired / Lapsed US ⏱️ 0.0 years remaining

Araliphatic ketones and carbinols

Assignee: Boehringer Ingelheim GmbH
•
Filing: 1974-12-12
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Granted: 1976-04-13
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Expires: 1994-12-12
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Abstract

Abstract Compounds of the formula WHEREIN R1 is isobutyl, phenyl, o-fluoro-phenyl, o-chloro-phenyl, cyclopentyl, cyclohexyl, methyl-cyclo-hexyl or cycloheptyl, R2 is hydrogen, fluorine, chlorine or bromine, R3 is methyl, ethyl or, when R1 is phenyl, fluoro-phenyl or chloro-phenyl, or R1 is cyclohexyl and R2 is halogen, also hydrogen, Z1 and Z2 are hydrogen or together form an additional carbon-to-carbon bond, A is O PARALLEL -C- or HOH ANGLE -C- and M IS 2, 4, 6, 8 OR WHEN R1 is halo-phenyl, isobutyl, cyclohexyl, methyl-cyclohexyl, cyclopentyl or cycloheptyl and/or R2 is halogen and/or R3 is methyl or ethyl and/or A is -CH(OH)-, also O; the compounds are useful as antiphlogistics.

Inventors

  • 👤 Wolfhard Engel
  • 👤 Josef Nickl
  • 👤 Helmut Teufel
  • 👤 Gunther Engelhardt
  • 👤 Ernst Seeger
  • 👤 Gunter Trummlitz

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 15:57
CPC Classifications
C; C07; C07C; C07C29/00; C07C29/132; C07C29/136; C07C29/143; C07C29/145; C07C29/17; C07C29/175; C07C29/36; C07C29/38; C07C29/40; C07C33/00; C07C33/18; C07C33/24; C07C33/28; C07C33/30; C07C33/34; C07C33/38; C07C33/40; C07C33/46; C07C33/48; C07C33/483; C07C33/486; C07C33/50; C07C45/00; C07C45/004; C07C45/27; C07C45/29; C07C45/51; C07C45/511; C07C45/513; C07C45/61; C07C45/62; C07C45/67; C07C45/68; C07C45/72; C07C45/74; C07C49/00; C07C49/20; C07C49/213; C07C49/215; C07C49/217; C07C49/225; C07C49/227; C07C49/233; C07C49/235; C07C49/237; C25; C25B; C25B3/00; C25B3/01; C25B3/07; C25B3/11; C25B3/20; C25B3/25; C07B; C07B2200/00; C07B2200/09; C07C2601/00; C07C2601/12; C07C2601/14; C07C2601/18

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 68 words
A compound of the formula ##SPC24## wherein R 1 is phenyl, o-fluoro-phenyl or o-chloro-phenyl, R 2 is hydrogen, fluorine, chlorine or bromine, R 3 is hydrogen, methyl, or ethyl, Z 1 and Z 2 are each hydrogen or together form an additional carbon-to-carbon bond, and m is 2,4,6,8 or, when R 1 is halo-phenyl and/or R 2 is halogen and/or R 3 is methyl or ethyl, also O.
Claim 2
Dependent Claim 68 words
A compound of the formula ##SPC24## wherein R 1 is phenyl, o-fluoro-phenyl or o-chloro-phenyl, R 2 is hydrogen, fluorine, chlorine or bromine, R 3 is hydrogen, methyl, or ethyl, Z 1 and Z 2 are each hydrogen or together form an additional carbon-to-carbon bond, and m is 2,4,6,8 or, when R 1 is halo-phenyl and/or R 2 is halogen and/or R 3 is methyl or ethyl, also O.
Claim 3
Dependent Claim 8 words
The compound of claim 1 which is 6-(2-fluoro-4-biphenylyl)-2-hexanone.
Claim 4
Dependent Claim 8 words
The compound of claim 1 which is 4-(4-biphenylyl)-2-pentanone.
Claim 5
Dependent Claim 8 words
The compound of claim 1 which is 8-(2'-fluoro-4-biphenylyl)-2-octanone.
Claim 6
Dependent Claim 8 words
The compound of claim 1 which is (E)-4-(4-biphenylyl)-3-pentene-2-one.
Claim 7
Dependent Claim 8 words
The compound of claim 1 which is (E)-4-(2'-fluoro-4-biphenylyl)-2-pentene-2-one.
Claim 8
Dependent Claim 9 words
The compound of claim 1 which is (E) -4-(2'-fluoro-4-biphenylyl)-3-pentene-2-one.

References Cited (Backward Citations)

US3702343A Cited
US3859256A Cited
US3879449A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-04-13 1979-10-13 1980-04-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-04-13 1983-10-13 1984-04-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-04-13 1987-10-13 1988-04-13 $7700.00 Window Closed / Lapsed

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