US3948898A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1,3-Dioxo-2-aminoalkyl-4,4-dimethyl-isoquinolines and salts thereof
Assignee: Boehringer Ingelheim GmbH
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Filing: 1974-09-04
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Granted: 1976-04-06
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Expires: 1994-09-04
Abstract
Abstract Compounds of the formula WHEREIN R1 is hydrogen, halogen, methoxy or methylthio R2 is hydrogen or methoxy, N IS 2 OR 3, AND A is OR WHERE R3 is hydrogen or methyl, R4 is pyridyl, methy-pyridyl, phenyl, chlorophenyl, trifluoromethyl-phenyl, tolyl, xylyl, ethyl-phenyl, diethyl-phenyl, methoxy-phenyl or dimethoxy-phenyl, and R5 and R6, which may be identical to or different from each other, are each hydrogen or methoxy, AND NON-TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF; THE COMPOUNDS AS WELL AS THE SALTS ARE USEFUL AS HYPOTENSIVES, SEDATIVES, ANTIARRHYTHMICS AND BRADYCARDIACS.
Inventors
- 👤 Eberhard Kutter
- 👤 Volkard Austel
- 👤 Wolfgang Eberlein
- 👤 Joachim Heider
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 00:53
CPC Classifications
C; C07; C07D; C07D217/00; C07D217/22; C07D217/24; A; A61; A61P; A61P25/00; A61P25/20; A61P9/00; A61P9/06; A61P9/12
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
33 words
A compound of the formula ##SPC15## wherein R 1 is hydrogen, halogen, methoxy or methylthio, R 2 is hydrogen or methoxy, n is 2 or 3, R 3 is hydrogen or methyl, and
Claim 2
Dependent Claim
33 words
A compound of the formula ##SPC15## wherein R 1 is hydrogen, halogen, methoxy or methylthio, R 2 is hydrogen or methoxy, n is 2 or 3, R 3 is hydrogen or methyl, and
Claim 3
Dependent Claim
24 words
R 4 is pyridyl, methyl-pyridyl, phenyl, chlorophenyl, trifluoromethyl-phenyl, tolyl, xylyl, ethyl-phenyl, diethyl-phenyl, methoxy-phenyl or dimethoxy-phenyl, or a non-toxic, pharmacologically acceptable acid addition salt thereof.
Claim 4
Dependent Claim
24 words
R 4 is pyridyl, methyl-pyridyl, phenyl, chlorophenyl, trifluoromethyl-phenyl, tolyl, xylyl, ethyl-phenyl, diethyl-phenyl, methoxy-phenyl or dimethoxy-phenyl, or a non-toxic, pharmacologically acceptable acid addition salt thereof.
Claim 5
Dependent Claim
17 words
A compound of claim 1, which is 1-[4,4-dimethyl-1,3-dioxo-(2H,4H)-isoquinolin-2-yl]-2-[4-(2-methoxy-phenyl)piperazin-1-yl]-ethane or a non-toxic, pharmacologically acceptable acid addition salt thereof.
References Cited (Backward Citations)
US3726875A
Cited
US3870721A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-04-06 | 1979-10-06 | 1980-04-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-04-06 | 1983-10-06 | 1984-04-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-04-06 | 1987-10-06 | 1988-04-06 | $7700.00 | Window Closed / Lapsed |