US3948885A
Expired / Lapsed
US
⏱️ 0.0 years remaining
5-Hydroxyl-1,2,3-triazole-4-carboxamide nucleoside
Assignee: Viratek Inc
•
Filing: 1973-03-19
•
Granted: 1976-04-06
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Expires: 1993-03-19
Abstract
Abstract A 5-hydroxy-1,2,3-triazole-4-carboxamide nucleoside, related to the C-nucleoside pyrazomycin, is facilely synthesized by condensation of acyl-blocked ribofuranose with trimethylsilylated 5-hydroxy-1,2,3-triazole-4-carboxamide or, alternatively, by cycloaddition of suitably blocked β-D-ribofuranosyl azide and the anion of ethyl malonamate, and demonstrated to exhibit antiviral properties. The triazole precursor of the former route, as well as certain of its novel salts, are also disclosed as potential antiviral agents.
Inventors
- 👤 Joseph T. Witkowski
- 👤 Roland K. Robins
- 👤 Frank A. Lehmkuhl
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 03:20
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/056
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
1 words
5-Hydroxy-1-β-D-ribofuranosyl-1,2,3-triazole-4-carboxamide.
Claim 2
Dependent Claim
1 words
5-Hydroxy-1-β-D-ribofuranosyl-1,2,3-triazole-4-carboxamide.
Claim 3
Dependent Claim
8 words
The 5'-phosphate of the compound of claim 1.
References Cited (Backward Citations)
US3470196A
Cited
US3598807A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-04-06 | 1979-10-06 | 1980-04-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-04-06 | 1983-10-06 | 1984-04-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-04-06 | 1987-10-06 | 1988-04-06 | $7700.00 | Window Closed / Lapsed |