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US3946231A Expired / Lapsed US ⏱️ 0.0 years remaining

Liquid scintillation counting system with automatic gain correction

Assignee: TM ANALYTIC Inc AN IL CORP
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Filing: 1968-06-12
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Granted: 1976-03-23
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Expires: 1988-06-12
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Abstract

Abstract Automatic liquid scintillation counting apparatus including a scintillating medium in the elevator ram of the sample changing apparatus. An appropriate source of radiation, which may be the external source for standardizing samples, produces reference scintillations in the scintillating medium which may be used for correction of the gain of the counting system.

Inventors

  • 👤 Richard B. Frank

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 02:48
CPC Classifications
G; G01; G01T; G01T1/00; G01T1/36; G01T1/40; G01T1/16; G01T1/20; G01T1/204; G01T7/00; G01T7/08

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 208 words
In an automatic liquid scintillation counting system, conveyor means for delivering a plurality of liquid scintillation samples to a sample transfer station; shielding means positioned adjacent same sample transfer station and defining a counting chamber spaced from said station and a passageway interconnecting said station and said chamber; transducer means associated with said counting chamber for converting scintillations within said chamber into electrical pulses corresponding in amplitude to the intensities of said scintillations; sample transfer means operatively associated with said counting chamber and said passageway and including an elevator ram adapted to traverse said counting chamber and said passageway for transporting said samples between said sample transfer station and said chamber; scintillation means operatively associated with said sample transfer means for automatically producing reference scintillations in said counting chamber when said samples are positioned outside said chamber by said sample transfer means and including a body of scintillating phosphor mounted in said elevator ram in a position such that said body is exposed to said transducer means in said counting chamber when an upper portion of said elevator ram is positioned within said passageway; and circuit means operatively associated with said transducer means for automatically adjusting the gain of said counting system in accordance with said reference scintillations.
Claim 2
Dependent Claim 208 words
In an automatic liquid scintillation counting system, conveyor means for delivering a plurality of liquid scintillation samples to a sample transfer station; shielding means positioned adjacent same sample transfer station and defining a counting chamber spaced from said station and a passageway interconnecting said station and said chamber; transducer means associated with said counting chamber for converting scintillations within said chamber into electrical pulses corresponding in amplitude to the intensities of said scintillations; sample transfer means operatively associated with said counting chamber and said passageway and including an elevator ram adapted to traverse said counting chamber and said passageway for transporting said samples between said sample transfer station and said chamber; scintillation means operatively associated with said sample transfer means for automatically producing reference scintillations in said counting chamber when said samples are positioned outside said chamber by said sample transfer means and including a body of scintillating phosphor mounted in said elevator ram in a position such that said body is exposed to said transducer means in said counting chamber when an upper portion of said elevator ram is positioned within said passageway; and circuit means operatively associated with said transducer means for automatically adjusting the gain of said counting system in accordance with said reference scintillations.
Claim 3
Dependent Claim 35 words
Apparatus as claimed in claim 1, wherein said scintillation means further includes a source of reference radiation permanently associated with said body of scintillating phosphor to produce said reference scintillations therein on a continuous basis.
Claim 4
Dependent Claim 37 words
Apparatus as claimed in claim 2, wherein said scintillating phosphor is a liquid scintillating phosphor, and said source of reference radiation is a radioactive source of alpha particles at least partially dissolved in said liquid scintillating phosphor.
Claim 5
Dependent Claim 37 words
Apparatus as claimed in claim 2, herein said scintillating phosphor is a solid scintillating medium, and said source of reference radiation is a radioactive source of alpha particles at least partially dispersed in said solid scintillating medium.
Claim 6
Dependent Claim 50 words
Apparatus as claimed in claim 1, wherein said scintillation means further includes a source of reference radiation adapted to produce said reference scintillations in said body of scintillating phosphor, and means for exposing said body of scintillating phosphor to said reference radiation when said body is within said counting chamber.
Claim 7
Dependent Claim 79 words
Apparatus as claimed in claim 5, wherein said body of scintillating phosphor is a solid scintillation crystal; said source of reference radiation comprises a rod having a radioactive source mounted thereto; and said elevator ram includes a first aperture receiving said crystal and a second aperture communicating with said first aperture and removably receiving said rod; said means for exposing including means for inserting said rod in said second aperture when said crystal is positioned within said counting chamber.
Claim 8
Dependent Claim 205 words
In an automatic liquid scintillation counting system, conveyor means for delivering a plurality of liquid scintillation samples to a sample transfer station; shielding means positioned adjacent said sample transfer station and defining a counting chamber spaced from said station and a passageway interconnecting said station and said chamber; transducer means associated with said counting chamber for converting scintillations therein having a spectrum of intensities into electrical pulses having a spectrum of amplitudes directly corresponding to said spectrum of intensities in accordance with the gain value of said transducer means; sample transfer means for transporting said samples between said sample transfer station and said counting chamber, including an elevator ram traversing said chamber and said passageway; said elevator ram having a platform on the top thereof on which said samples ride and having a solid scintillation crystal mounted therein at a location beneath said platform such that said crystal is positioned within said chamber when a sample on said platform is without said chamber; and means for alternatively exposing said samples and said crystal to a source of penetrating reference radiations when said samples and said crystal are within said sample counting chamber to produce efficiency-correction scintillations in said samples and reference scintillations in said crystal.
Claim 9
Dependent Claim 205 words
In an automatic liquid scintillation counting system, conveyor means for delivering a plurality of liquid scintillation samples to a sample transfer station; shielding means positioned adjacent said sample transfer station and defining a counting chamber spaced from said station and a passageway interconnecting said station and said chamber; transducer means associated with said counting chamber for converting scintillations therein having a spectrum of intensities into electrical pulses having a spectrum of amplitudes directly corresponding to said spectrum of intensities in accordance with the gain value of said transducer means; sample transfer means for transporting said samples between said sample transfer station and said counting chamber, including an elevator ram traversing said chamber and said passageway; said elevator ram having a platform on the top thereof on which said samples ride and having a solid scintillation crystal mounted therein at a location beneath said platform such that said crystal is positioned within said chamber when a sample on said platform is without said chamber; and means for alternatively exposing said samples and said crystal to a source of penetrating reference radiations when said samples and said crystal are within said sample counting chamber to produce efficiency-correction scintillations in said samples and reference scintillations in said crystal.
Claim 10
Dependent Claim 82 words
Apparatus as claimed in claim 7, wherein said elevator ram defines a first aperture beneath said platform and a second aperture beneath said solid scintillation crystal; and said means for alternatively exposing said samples and said crystal includes means for supporting a radioactive source in disoperative association with respect to said samples and said crystal, and means for alternatively inserting said radioactive source into said first and second apertures when said samples and said crystal, respectively, are positioned within said counting chamber.
Claim 11
Dependent Claim 50 words
Apparatus as claimed in claim 7, further comprising circuit means operatively associated with said transducer means to produce a sample activity count and an efficiency-correction count for each of said samples and to adjust the overall gain of said counting system in accordance with said reference scintillations in said crystal.

References Cited (Backward Citations)

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US3101409A Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-03-23 1979-09-22 1980-03-23 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-03-23 1983-09-22 1984-03-23 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-03-23 1987-09-22 1988-03-23 $7700.00 Window Closed / Lapsed

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