US3946111A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical compositions containing 1 or 2-mono and dialkyl substituted thienobenzopyrans and pharmacological uses thereof
Assignee: Sharps Associates
•
Filing: 1974-11-18
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Granted: 1976-03-23
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Expires: 1994-11-18
Abstract
Abstract 1,2-Dihydro-4H-thieno-[2,3-c][1]benzopyrans of the formulae WHEREIN R is a lower alkyl group having 1 to 5 carbons, R1 is hydrogen or a lower alkyl group having 1 to 5 carbons, R2 is a lower alkyl group and R3 is an alkyl group having 1 to 20 carbon atoms, a phenyl-lower alkyl group or a cycloalkyl-lower alkyl group. The compounds have analgesic, antihypertensive, antidepressant, anticonvulsant, antianxiety, sedative-hypnotic and/or tranquilization activity.
Inventors
- 👤 Martin Winn
- 👤 Raj Kumar Razdan
- 👤 Haldean Cloyce Dalzell
- 👤 Joyce Ruth Krei
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 23:20
CPC Classifications
C; C07; C07D; C07D333/00; C07D333/02; C07D333/04; C07D333/26; C07D333/38
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
98 words
A pharmaceutical composition in unit dosage form containing 2 to 300 mg. of a compound of the formulae ##SPC20## and ##SPC21## wherein R is lower alkyl having 1 to 5 carbons, R 1 is hydrogen or lower alkyl having 1 to 5 carbons, R 2 is lower alkyl and R 3 is alkyl having 1 to 20 carbon atoms, a phenyl-lower alkyl in which the phenyl is unsubstituted or is substituted with a lower-alkyl, lower-alkoxy, halo, nitro or lower-alkylmercapto group, or a cycloalkyl-lower alkyl group in which the cycloalkyl contains 3 to 8 carbons in the ring, and
Claim 2
Dependent Claim
98 words
A pharmaceutical composition in unit dosage form containing 2 to 300 mg. of a compound of the formulae ##SPC20## and ##SPC21## wherein R is lower alkyl having 1 to 5 carbons, R 1 is hydrogen or lower alkyl having 1 to 5 carbons, R 2 is lower alkyl and R 3 is alkyl having 1 to 20 carbon atoms, a phenyl-lower alkyl in which the phenyl is unsubstituted or is substituted with a lower-alkyl, lower-alkoxy, halo, nitro or lower-alkylmercapto group, or a cycloalkyl-lower alkyl group in which the cycloalkyl contains 3 to 8 carbons in the ring, and
Claim 3
Independent Claim
31 words
The method of inducing analgesia in an animal which comprises administering to the animal a safe but effective amount of 1,2-dihydro-1,4,4-trimethyl-9-hydroxy-7-(3-methyl-2-octyl)-4H-thieno-[2,3-c][1] benzopyran or 1,2-dihydro-2,4,4-trimethyl-9-hydroxy-7-(3-methyl-2-octyl)-4H-thieno-[2,3-c][1] benzopyran to effect analgesia in the animal.
Claim 4
Independent Claim
31 words
The method of inducing analgesia in an animal which comprises administering to the animal a safe but effective amount of 1,2-dihydro-1,4,4-trimethyl-9-hydroxy-7-(3-methyl-2-octyl)-4H-thieno-[2,3-c][1] benzopyran or 1,2-dihydro-2,4,4-trimethyl-9-hydroxy-7-(3-methyl-2-octyl)-4H-thieno-[2,3-c][1] benzopyran to effect analgesia in the animal.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-03-23 | 1979-09-22 | 1980-03-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-03-23 | 1983-09-22 | 1984-03-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-03-23 | 1987-09-22 | 1988-03-23 | $7700.00 | Window Closed / Lapsed |