US3943173A
Expired / Lapsed
US
⏱️ 0.0 years remaining
3-Alkylamino- alpha-aminomethyl-4-hydroxybenzyl alcohols
Assignee: GlaxoSmithKline LLC
•
Filing: 1972-11-22
•
Granted: 1976-03-09
•
Expires: 1992-11-22
Abstract
Abstract A series of 3-alkylamino-α-substituted aminomethyl-4-hydroxybenzyl alcohols are prepared. These compounds are β-adrenergic stimulants, in particular as bronchodilators.
Inventors
- 👤 Donald F. Colella
- 👤 Carl Kaiser
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 08:16
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/13; A61K31/135
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
45 words
A compound of the formula ##SPC3## wherein R and R 1 are each hydrogen or C 1 -C 4 alkyl; R 2 is hydrogen, methyl, or ethyl; and R 3 is isopropyl, t-butyl, cyclobutyl, 1-(p-hydroxybenzyl) ethyl, or 2-(p-hydroxybenzyl)-isopropyl or a pharmaceutically acceptable nontoxic salt thereof.
Claim 2
Dependent Claim
45 words
A compound of the formula ##SPC3## wherein R and R 1 are each hydrogen or C 1 -C 4 alkyl; R 2 is hydrogen, methyl, or ethyl; and R 3 is isopropyl, t-butyl, cyclobutyl, 1-(p-hydroxybenzyl) ethyl, or 2-(p-hydroxybenzyl)-isopropyl or a pharmaceutically acceptable nontoxic salt thereof.
Claim 3
Dependent Claim
12 words
A compound as claimed in claim 1 where R 2 is hydrogen.
Claim 4
Dependent Claim
12 words
A compound as claimed in claim 2 where R 1 is hydrogen.
Claim 5
Dependent Claim
12 words
A compound as claimed in claim 2 where R 3 is t-butyl.
Claim 6
Dependent Claim
12 words
A compound as claimed in claim 4 being the compound α-(t-butylaminemethyl)-4-hydroxy-3-methylaminobenzyl alcohol.
Claim 7
Dependent Claim
12 words
A compound as claimed in claim 2 being the compound α-(t-butylaminemethyl)-3-dimethylamino-4-hydroxybenzyl alcohol.
References Cited (Backward Citations)
US2393820A
Cited
US3818101A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-03-09 | 1979-09-08 | 1980-03-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-03-09 | 1983-09-08 | 1984-03-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-03-09 | 1987-09-08 | 1988-03-09 | $7700.00 | Window Closed / Lapsed |