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US3937733A Expired / Lapsed US ⏱️ 0.0 years remaining

Salts of iodomethanesulfonic acid with organic bases

Assignee: Bayer Pharma AG
•
Filing: 1972-03-31
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Granted: 1976-02-10
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Expires: 1992-03-31
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Abstract

Abstract Salts of iodomethanesulfonic acid and an organic base, more particularly, glucamine, N-alkyl- and N, N-dialkylglucamines and N-hydroxyalkyl- and N,N-di-hydroxyalkylglucamines, are useful as X-ray contrast agents, especially for spinal X-ray examination.

Inventors

  • 👤 Hermann Ulbrich
  • 👤 Wolfgang Beich

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 00:22
CPC Classifications
A; A61; A61K; A61K49/00; A61K49/04; A61K49/0433

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 54 words
A myelographic salt of iodomethanesulfonic acid with an amine selected from the group consisting of glucamine, N-alkylglucamine, N,N-dialkylglucamine and hydroxyalkylglucamines of the latter and former alkylglucamines containing more than one carbon atom in the alkyl radical, said amine in all cases having up to a total of four carbon atoms in the alkyl portion.
Claim 2
Dependent Claim 54 words
A myelographic salt of iodomethanesulfonic acid with an amine selected from the group consisting of glucamine, N-alkylglucamine, N,N-dialkylglucamine and hydroxyalkylglucamines of the latter and former alkylglucamines containing more than one carbon atom in the alkyl radical, said amine in all cases having up to a total of four carbon atoms in the alkyl portion.
Claim 3
Dependent Claim 24 words
A salt of claim l, wherein the amine is selected from the group consisting of N-methylglucamine; N,N-dimethylglucamine; N-ethylglucamine; N-methyl,N-ethylglucamine; N,N-diethylglucamine; N-β-hydroxyethylglucamine; N-methyl,N-β-hydroxyethylglucamine and N,N-di-β-hydroxyethylglucamine.
Claim 4
Dependent Claim 11 words
A salt of claim 1, wherein said amine is an N-alkylglucamine.
Claim 5
Dependent Claim 11 words
A salt of claim 1, wherein said amine is an N,N-dialkylglucamine.
Claim 6
Dependent Claim 11 words
A salt of claim 1, wherein said amine is an N-hydroxyalkylglucamine.
Claim 7
Dependent Claim 11 words
A salt of claim 1, wherein said amine is an N,N-dihydroxyalkylglucamine.
Claim 8
Dependent Claim 36 words
A salt of claim 1, selected from the group consisting of the N-methylglucamine salt of iodomethanesulfonic acid, the N,N-dimethylglucamine salt of iodomethanesulfonic acid, the N-hydroxyethylglucamine salt of iodomethanesulfonic acid and the glucamine salt of iodomethanesulfonic acid.
Claim 9
Dependent Claim 11 words
A salt of claim 7, the N-methylglucamine salt of iodomethanesulfonic acid.
Claim 10
Dependent Claim 11 words
A salt of claim 7, the N,N-dimethylglucamine salt of iodomethanesulfonic acid.
Claim 11
Dependent Claim 11 words
A salt of claim 7, the N-β-hydroxyethylglucamine salt of iodomethanesulfonic acid.
Claim 12
Dependent Claim 11 words
A salt of claim 7, the glucamine salt of iodomethanesulfonic acid.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-02-09 1979-08-11 1980-02-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-02-09 1983-08-11 1984-02-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-02-09 1987-08-11 1988-02-10 $7700.00 Window Closed / Lapsed

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