US3937668A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for incorporating substances into protein microspheres
Assignee: Individual
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Filing: 1972-11-06
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Granted: 1976-02-10
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Expires: 1992-11-06
Abstract
Abstract The subject matter of this invention is a process for solid albumin particles so that such spheric particles may act as a carrier for radioactivity, drugs, insecticides, dyes, metal salts, etc. In order to prepare such spheric particles, the substance to be incorporated therein is transformed into a precipitate. This precipitate is then mixed with an aqueous solution of albumin. The mixture thus prepared is then injected into cotton seed oil while stirring so as to obtain a fine dispersion of the albumin droplets and the precipitate in the oil, then the mixture is heated above 100°C to evaporate water and to form spheric albumin particles having the precipitate encapsulated therein.
Inventors
- 👤 Ilse Zolle
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 08:25
CPC Classifications
B; B01; B01J; B01J13/00; B01J13/02; A; A01; A01N; A01N25/00; A01N25/26; A01N25/28; A61; A61K; A61K9/00; A61K9/14; A61K9/16; A61K9/1605; A61K9/1629; A61K9/1658; Y; Y10; Y10S; Y10S436/00; Y10S436/829; Y10T; Y10T428/00; Y10T428/29; Y10T428/2982; Y10T428/2984
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
85 words
A process for incorporating a substance capable of being precipitated into albumin millimicrospheres comprising: preparing a precipitate of said substance and forming a mixture of the precipitate with an aqueous solution of albumin; injecting said mixture into oil and pressing the resultant through a fine capillary or rotating disc to form an extremely fine emulsion of droplets of the precipitate and albumin in said oil, heating said oily mixture above 100°C and separating the formed albumin millimicrospheres from said oil having said precipitate encapsulated therein.
Claim 2
Dependent Claim
85 words
A process for incorporating a substance capable of being precipitated into albumin millimicrospheres comprising: preparing a precipitate of said substance and forming a mixture of the precipitate with an aqueous solution of albumin; injecting said mixture into oil and pressing the resultant through a fine capillary or rotating disc to form an extremely fine emulsion of droplets of the precipitate and albumin in said oil, heating said oily mixture above 100°C and separating the formed albumin millimicrospheres from said oil having said precipitate encapsulated therein.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-02-09 | 1979-08-11 | 1980-02-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-02-09 | 1983-08-11 | 1984-02-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-02-09 | 1987-08-11 | 1988-02-10 | $7700.00 | Window Closed / Lapsed |