US3932653A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Composition and method for topical administration of griseofulvin
Assignee: Whitby Research Inc
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Filing: 1974-12-19
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Granted: 1976-01-13
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Expires: 1994-12-19
Abstract
Abstract There is disclosed a method for topically administering griseofulvin to a human or animal in a manner such that a high degree of epidermal, especially stratum corneum, retention of griseofulvin is attained by contacting the skin of a human or animal with an effective amount of a therapeutic composition containing griseofulvin and 2-pyrrolidone or an N-lower alkyl-2-pyrrolidone.
Inventors
- 👤 Richard B. Stoughton
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 11:05
CPC Classifications
A; A61; A61Q; A61Q3/00; A61K; A61K31/00; A61K31/33; A61K31/335; A61K31/34; A61K47/00; A61K47/06; A61K47/22; A61K8/00; A61K8/18; A61K8/30; A61K8/49; A61K8/4906; A61K8/4913; A61K8/4973; A61K9/00; A61K9/0012; A61K9/0014; A61Q19/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
50 words
A composition useful in the topical treatment of fungal infections of the skin and nails comprising about 0.1 to about 10 percent by weight of griseofulvin together with about 5 to about 99.9 percent by weight of a compound selected from the group consisting of 2-pyrrolidone and an N-lower alkyl-2-pyrrolidone.
Claim 2
Dependent Claim
50 words
A composition useful in the topical treatment of fungal infections of the skin and nails comprising about 0.1 to about 10 percent by weight of griseofulvin together with about 5 to about 99.9 percent by weight of a compound selected from the group consisting of 2-pyrrolidone and an N-lower alkyl-2-pyrrolidone.
Claim 3
Dependent Claim
14 words
The composition of claim 1 wherein the N-lower alkyl substitutent has 1-4 carbon atoms.
Claim 4
Dependent Claim
38 words
A composition useful in the topical treatment of fungal infections of the skin and nails comprising about 0.1 to about 10 percent by weight of griseofulvin together with about 5 to about 99.9 percent by weight of N-methyl-2-pyrrolidone.
Claim 5
Dependent Claim
38 words
A composition useful in the topical treatment of fungal infections of the skin and nails comprising about 0.1 to about 10 percent by weight of griseofulvin together with about 5 to about 99.9 percent by weight of N-methyl-2-pyrrolidone.
Claim 6
Independent Claim
66 words
A method for effectively administering a therapeutic amount of griseofulvin topically to humans or animals comprising contacting human or animal skin or nails with an effective amount of a therapeutic composition containing about 0.1 to about 10 percent by weight of griseofulvin together with about 5 to about 99.9 percent by weight of a compound selected from the group consisting of 2-pyrrolidone and an N-lower alkyl-2-pyrrolidone.
Claim 7
Independent Claim
66 words
A method for effectively administering a therapeutic amount of griseofulvin topically to humans or animals comprising contacting human or animal skin or nails with an effective amount of a therapeutic composition containing about 0.1 to about 10 percent by weight of griseofulvin together with about 5 to about 99.9 percent by weight of a compound selected from the group consisting of 2-pyrrolidone and an N-lower alkyl-2-pyrrolidone.
Claim 8
Dependent Claim
14 words
The method of claim 4 wherein the N-lower alkyl substituent has 1-4 carbon atoms.
Claim 9
Dependent Claim
10 words
The method of claim 4 wherein the compound is N-methyl-2-pyrrolidone.
References Cited (Backward Citations)
US3773959A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-01-12 | 1979-07-14 | 1980-01-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-01-12 | 1983-07-14 | 1984-01-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-01-12 | 1987-07-14 | 1988-01-13 | $7700.00 | Window Closed / Lapsed |