US3929576A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Producing 3-fluoro-D-alanine
Assignee: Merck and Co Inc
•
Filing: 1974-11-20
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Granted: 1975-12-30
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Expires: 1994-11-20
Abstract
Abstract 3-Fluoro-D-alanine and its deutero analogs, which are potent antibacterial agents, are prepared from fluoropyruvic acid by asymmetric synthesis using an optically active amine such as DAlpha -methylbenzylamine.
Inventors
- 👤 Donald F Reinhold
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 15:22
CPC Classifications
C; C12; C12P; C12P13/00; C12P13/04; C07; C07C; C07C229/00; C07C229/02; C07C229/04; C07C229/20; C12P13/06; C12P13/22; C12P13/222; C12P13/24; C12P17/00; C12P17/10
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
25 words
THE PROCESS WHICH COMPRISES ENZYMATICALLY TRANSFERRING AN AMINO GROUP OF A D-AMINO ACID FOR THE KETO GROUP OF FLUOROPYRUVIC ACID THEREBY FORMING THE CORRESPONDING 3FLUORO-D-ALANINE.
Claim 2
Dependent Claim
25 words
THE PROCESS WHICH COMPRISES ENZYMATICALLY TRANSFERRING AN AMINO GROUP OF A D-AMINO ACID FOR THE KETO GROUP OF FLUOROPYRUVIC ACID THEREBY FORMING THE CORRESPONDING 3FLUORO-D-ALANINE.
Claim 3
Dependent Claim
23 words
The process as defined in claim 1, wherein the enzyme utilized is a D-amino acid oxidase, and the D-amino acid employed is D-proline.
References Cited (Backward Citations)
US2749279A
Cited
US3183170A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-12-29 | 1979-06-30 | 1979-12-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-12-29 | 1983-06-30 | 1983-12-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-12-29 | 1987-06-30 | 1987-12-30 | $7700.00 | Window Closed / Lapsed |