US3928598A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug
Assignee: Eli Lilly and Co
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Filing: 1973-11-05
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Granted: 1975-12-23
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Expires: 1993-11-05
Abstract
Abstract Use of 1-hydroxy-3-alkyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo(b, d)pyran-9-ones as psychotropic drugs, particularly as antianxiety and/or anti-depressant drugs, as sedative and/or analgesic drugs, and pharmaceutical compositions containing same.
Inventors
- 👤 Robert A Archer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:29
CPC Classifications
C; C07; C07D; C07D311/00; C07D311/02; C07D311/78; C07D311/80; A; A61; A61P; A61P25/00; A61P25/04; A61P25/20; A61P25/24; A61P25/26; C07C; C07C49/00; C07C49/587; C07C49/703; C07C49/747
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
28 words
A PROCESS FOR TREATING MAMMALS SUFFERING FOR ANXIETY WHICH COMPRISES ADMINISTERING TO A MAMMAL IN NEED OF SUCH TREATMENT A DOSE OF A COMPOUND REPRESENTED BY THE FORMULA
Claim 2
Dependent Claim
28 words
A PROCESS FOR TREATING MAMMALS SUFFERING FOR ANXIETY WHICH COMPRISES ADMINISTERING TO A MAMMAL IN NEED OF SUCH TREATMENT A DOSE OF A COMPOUND REPRESENTED BY THE FORMULA
Claim 3
Dependent Claim
23 words
A process according to claim 1 in which a dose of from 0.1 to 100 mgs per day of the drug is administered.
Claim 4
Dependent Claim
23 words
A process according to claim 1 in which a dose of from 1 to 20 mgs. per day of the drug is administered.
Claim 5
Dependent Claim
16 words
A process according to claim 1 in which the drug is administered by the oral route.
Claim 6
Dependent Claim
16 words
A process according to claim 1 in which dl-trans-1-hydroxy-3-(1'',1''-dimethylheptyl)-6,6a Beta ,7,8,10,10a Alpha -hexahydro-6, 6-dimethyl-9H-dibenzo(b,d)pyran-9-one is administered.
Claim 7
Dependent Claim
16 words
A process according to claim 1 in which dl-trans-1-hydroxy-3-(1'',2''-dimethylheptyl)-6,6a Beta ,7,8,10,10a Alpha -hexahydro-6, 6-dimethyl-9H-dibenzo(b,d)pyran-9-one is administered.
Claim 8
Dependent Claim
15 words
A process according to claim 1 in which dl-trans-1-hydroxy-3-(1''-methylheptyl)-6,6a Beta ,7,8,10,10a Alpha -hexahydro-6,6-dimethyl-9H-dibenzo(b,d)pyran-9-one is administered.
Claim 9
Dependent Claim
33 words
A pharmaceutical composition, in unit dosage form, for the treatment of anxiety, consisting of a pharmaceutical carrier and, as a therapeutic agent, from 0.1 to 25 mg. of a compound of the formula
Claim 10
Dependent Claim
33 words
A pharmaceutical composition, in unit dosage form, for the treatment of anxiety, consisting of a pharmaceutical carrier and, as a therapeutic agent, from 0.1 to 25 mg. of a compound of the formula
Claim 11
Dependent Claim
19 words
A pharamceutical composition according to claim 8 in which dl-trans-1-hydroxy-3-(1'',1''-dimethylheptyl)-6,6a Beta ,7,8,10, 10a Alpha -hexahydro-,6,6-dimethyl-9H-dibenzo(b,d)pyran9-one is the therapeutic agent.
Claim 12
Dependent Claim
19 words
A pharmaceutical composition according to claim 8 in which dl-trans-1-hydroxy-3-(1'',2''-dimethylheptyl)-6,6a Beta ,7,8,10, 10a Alpha -hexahydro-6,6-dimethyl-9H-dibenzo(b,d)pyran9-one is the therapeutic agent.
Claim 13
Dependent Claim
18 words
A pharmaceutical composition according to claim 8 in which dl-trans-1-hydroxy-3-(1''-methylheptyl)-6,6a, Beta ,7,8,10,10a Alpha -hexahydro-6,6-dimethyl-9H-dibenzo(b,d)pyran-9-one is the therapeutic agent.
References Cited (Backward Citations)
US3507885A
Cited
US3636058A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-12-22 | 1979-06-23 | 1979-12-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-12-22 | 1983-06-23 | 1983-12-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-12-22 | 1987-06-23 | 1987-12-23 | $7700.00 | Window Closed / Lapsed |