US3928397A
Expired / Lapsed
US
⏱️ 0.0 years remaining
New 5-cholestene derivatives and preparation thereof
Assignee: Eisai Co Ltd
•
Filing: 1975-01-06
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Granted: 1975-12-23
•
Expires: 1995-01-06
Abstract
Abstract New 5-cholesten-3 Beta ,24,25- or 3 Beta ,25,26-triol and esters thereof, which are valuable intermediates for the production of active vitamin D3, are provided by a process wherein the protected 3 Beta -hydroxy-5,24- or -5,25-cholestadiene is treated with osmium tetroxide to form osmate ester thereof and the latter is decomposed to the corresponding 24,25- or 25,26-dihydroxy compound, and, if necessary, the 3 Beta -hydroxy-protected group thereof is splitt off to produce the 5-cholesten-triol and one or more of the hydroxy groups of the resulting products are esterified with acylating reagent.
Inventors
- 👤 Nobuo Ikekawa
- 👤 Masuo Morisaki
- 👤 Julieta Rubio Lightbourn
- 👤 Masao Seki
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 15:33
CPC Classifications
C; C07; C07J; C07J9/00; C07J1/00
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
6 words
5-CHOLESTENE DERIVATIVES REPRESENTED BY THE FORMULA:
Claim 2
Dependent Claim
6 words
5-CHOLESTENE DERIVATIVES REPRESENTED BY THE FORMULA:
Claim 3
Dependent Claim
4 words
5-Cholesten-3 Beta ,24,25-triol 3-acetate.
Claim 4
Dependent Claim
4 words
5-Cholesten-3 Beta ,24,25-triol 3-acetate.
Claim 5
Dependent Claim
4 words
5-Cholesten-3 Beta ,24,25-triol 3,24-diacetate.
Claim 6
Dependent Claim
4 words
5-Cholesten-3 Beta ,24,25-triol 3,24-diacetate.
Claim 7
Dependent Claim
4 words
5-Cholesten-3 Beta ,25,26-triol 3acetate.
Claim 8
Dependent Claim
4 words
5-Cholesten-3 Beta ,25,26-triol 3acetate.
Claim 9
Dependent Claim
3 words
5Cholesten-3 Beta ,24,25-triol.
Claim 10
Dependent Claim
3 words
5Cholesten-3 Beta ,24,25-triol.
Claim 11
Dependent Claim
3 words
5-Cholesten-3 Beta ,25,26-triol.
Claim 12
Dependent Claim
3 words
5-Cholesten-3 Beta ,25,26-triol.
Claim 13
Dependent Claim
6 words
5-Cholesten-3 Beta ,24,25-triol 3 Beta ,24-dibenzoate.
Claim 14
Dependent Claim
6 words
5-Cholesten-3 Beta ,24,25-triol 3 Beta ,24-dibenzoate.
Claim 15
Dependent Claim
6 words
5Cholesten-3 Beta ,24,25-triol 3 Beta ,24,25-tribenzoate.
Claim 16
Dependent Claim
6 words
5Cholesten-3 Beta ,24,25-triol 3 Beta ,24,25-tribenzoate.
Claim 17
Dependent Claim
4 words
25-Trimethylsilyloxy-5-cholesten-3 Beta ,24-diol dibenzoate.
Claim 18
Dependent Claim
4 words
25-Trimethylsilyloxy-5-cholesten-3 Beta ,24-diol dibenzoate.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-12-22 | 1979-06-23 | 1979-12-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-12-22 | 1983-06-23 | 1983-12-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-12-22 | 1987-06-23 | 1987-12-23 | $7700.00 | Window Closed / Lapsed |