US3923795A
Expired / Lapsed
US
⏱️ 0.0 years remaining
2-Alkoxycephalosporins
Assignee: Eli Lilly and Co
•
Filing: 1972-06-19
•
Granted: 1975-12-02
•
Expires: 1992-06-19
Abstract
Abstract Novel 2-alkoxycephalosporins exhibit antibiotic activity and are prepared by reacting a cephalosporin or 2-methylcephalosporin in the presence of a C1-C4 alkanol with a reagent which is a source of positive halogen.
Inventors
- 👤 Douglas O Spry
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 18:10
CPC Classifications
C; C07; C07D; C07D501/00; C07D501/02; C07D501/04; A; A61; A61P; A61P31/00; A61P31/04; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/582
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
12 words
A PROCESS FOR CONVERTING A CEPHALOSPORIN OR A 2-METHYLCEPHALOSPORIN OF THE FORMULA
Claim 2
Dependent Claim
12 words
A PROCESS FOR CONVERTING A CEPHALOSPORIN OR A 2-METHYLCEPHALOSPORIN OF THE FORMULA
Claim 3
Dependent Claim
19 words
Process of claim 1, in which R1 is hydrogen, C1-C4 alkyl, 2, 2,2-trichloroethyl, benzyl, benzhydryl, p-methoxybenzyl, p-nitrobenzyl, or phthalimidomethyl.
Claim 4
Dependent Claim
14 words
Process of claim 2, which comprises using chlorine as the source of positive halogen.
Claim 5
Dependent Claim
17 words
Process of claim 3, in which the C1-C4 alcohol is methanol, ethanol, isopropyl alcohol, or t-butyl alcohol.
Claim 6
Dependent Claim
21 words
Process of claim 4, in which the reaction is carried out at a temperature of from about -15*C. to about +40*C.
Claim 7
Dependent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 8
Dependent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 9
Dependent Claim
15 words
Compound of claim 6, in which R3 is hydrogen and R2 is hydrogen or acetoxy.
Claim 10
Dependent Claim
13 words
Compound of claim 7, in which R4 is methyl, ethyl, isopropyl, or t-butyl.
Claim 11
Dependent Claim
12 words
Compound of claim 8, in which R1 is hydrogen, p-nitrobenzyl, or 2,2,2-trichloroethyl.
Claim 12
Dependent Claim
9 words
Compound of claim 9, in which R is 2-thienylacetamido.
Claim 13
Dependent Claim
12 words
Compound of claim 9, in which R is Alpha -phenyl- Alpha aminoacetamido.
Claim 14
Dependent Claim
9 words
Compound of claim 9, in which R is phenoxyacetamido.
Claim 15
Dependent Claim
12 words
Process of claim 2, in which R1 is hydrogen or C1-C4 alkyl.
Claim 16
Dependent Claim
22 words
Process of claim 13, in which R is 2-thienylacetamido, R1 is hydrogen, R2 is acetoxy, R3 is hydrogen, and R4 is methyl.
Claim 17
Dependent Claim
12 words
Compound of claim 6, in which R1 is hydrogen or C1-C4 alkyl.
Claim 18
Dependent Claim
22 words
Compound of claim 15, in which R is 2-thienylacetamido, R1 is hydrogen, R2 is acetoxy, R3 is hydrogen, and R4 is methyl.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-12-01 | 1979-06-02 | 1979-12-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-12-01 | 1983-06-02 | 1983-12-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-12-01 | 1987-06-02 | 1987-12-02 | $7700.00 | Window Closed / Lapsed |