US3920840A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Treatment of psoriasis with n-methyldiethanolamine
Assignee: Individual
•
Filing: 1974-03-28
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Granted: 1975-11-18
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Expires: 1994-03-28
Abstract
Abstract A treatment to alleviate the symptoms of psoriasis consisting of topical application of a cream, ointment or lotion containing as the active ingredient N-methyldiethanolamine is disclosed. The therapeutic composition may include N-methyldiethanolamine present in a total amount of from about 0.5 to 5 percent by weight in either a cream or ointment, a water or alcohol solution. Topical application to affected areas has been found to achieve from substantial to complete remissions of psoriasis in humans.
Inventors
- 👤 Scott Eugene J Van
- 👤 Ruey J Yu
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 13:16
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/13; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K9/00; A61K9/0012; A61K9/0014
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
34 words
A COMPOSITION FOR THE TOPICAL TREATMENT OF PSORIASIS COMPRISING: 0.5 TO 5.0 PERCENT BY WEIGHT OF N-METHYLDIETHANOLAMINE IN ADMIXTURE WITH A MIXTURE OF WATER, ETHANOL, AND PROPYLENE GLYCOL IN A VOLUME RATIO OF 40:40:20.
Claim 2
Dependent Claim
34 words
A COMPOSITION FOR THE TOPICAL TREATMENT OF PSORIASIS COMPRISING: 0.5 TO 5.0 PERCENT BY WEIGHT OF N-METHYLDIETHANOLAMINE IN ADMIXTURE WITH A MIXTURE OF WATER, ETHANOL, AND PROPYLENE GLYCOL IN A VOLUME RATIO OF 40:40:20.
Claim 3
Dependent Claim
23 words
A composition for the topical treatment of psoriasis comprising: 0.5 to 5.0 percent by weight of N-Methyldiethanolamine in an admixture with hydrophilic ointment.
Claim 4
Dependent Claim
23 words
A composition for the topical treatment of psoriasis comprising: 0.5 to 5.0 percent by weight of N-Methyldiethanolamine in an admixture with hydrophilic ointment.
Claim 5
Dependent Claim
20 words
A composition for the treatment of psoriasis comprising: 0.5 to 5.0 percent by weight of N-methyldiethanolamine in admixture with petrolatum.
Claim 6
Dependent Claim
20 words
A composition for the treatment of psoriasis comprising: 0.5 to 5.0 percent by weight of N-methyldiethanolamine in admixture with petrolatum.
Claim 7
Dependent Claim
27 words
A composition for the topical treatment of psoriasis comprising 0.5 to 5.0 percent by weight of N-methyldiethanolamine in admixture with a mixture of petrolatum and liquid petrolatum.
Claim 8
Dependent Claim
27 words
A composition for the topical treatment of psoriasis comprising 0.5 to 5.0 percent by weight of N-methyldiethanolamine in admixture with a mixture of petrolatum and liquid petrolatum.
Claim 9
Dependent Claim
19 words
The composition of claim 1 wherein the N-methyldiethanolamine is present in from 0.5 to about 1 percent by weight.
Claim 10
Dependent Claim
16 words
The composition of claim 1 wherein the pH thereof is from about 5 to about 6.
Claim 11
Independent Claim
48 words
A method of treating psoriasis in a human suffering therefrom comprising the topical application to involved portions of the said human of an effective amount of a therapeutic composition containing from about 0.5 to about 5.0 percent by weight of N-methyldiethanolamine in admixture with a pharmaceutically acceptable carrier.
Claim 12
Independent Claim
48 words
A method of treating psoriasis in a human suffering therefrom comprising the topical application to involved portions of the said human of an effective amount of a therapeutic composition containing from about 0.5 to about 5.0 percent by weight of N-methyldiethanolamine in admixture with a pharmaceutically acceptable carrier.
Claim 13
Dependent Claim
19 words
The method of claim 7 wherein the N-methyldiethanolamine is present in from 0.5 to about 1 percent by weight.
Claim 14
Dependent Claim
18 words
The method of claim 7 wherein the pH of the composition is from about 5 to about 6.
Claim 15
Dependent Claim
52 words
The method of claim 7 wherein the carrier consists essentially of water, ethanol, and propylene glycol, the concentration of ethanol being not more than about 70 percent by weight of the total composition, and the concentration of propylene glycol being not more than about 30 percent by weight of the total composition.
Claim 16
Dependent Claim
24 words
The method of claim 7 wherein the carrier consists essentially of water, ethanol, and propylene glycol present in a volume ratio of 40:40:20, respectively.
Claim 17
Dependent Claim
10 words
The method of claim 7 wherein the carrier is petrolatum.
Claim 18
Dependent Claim
37 words
The method of claim 7 wherein the carrier includes a member selected from the group consisting of water and ethanol, present in a concentration of from 1 to about 20 percent by volume of the total composition.
Claim 19
Dependent Claim
20 words
The method of claim 13 wherein said member is present in about 10 percent by volume of the total composition.
Claim 20
Dependent Claim
18 words
The method of claim 7 wherein the carrier comprises a mixture of while solid petrolatum and liquid petrolatum.
Claim 21
Dependent Claim
12 words
The method of claim 7 wherein the carrier consists essentially of water.
Claim 22
Dependent Claim
18 words
The method of claim 7 wherein said composition is applied topically to psoriasis lesions at least once daily.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-11-17 | 1979-05-19 | 1979-11-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-11-17 | 1983-05-19 | 1983-11-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-11-17 | 1987-05-19 | 1987-11-18 | $7700.00 | Window Closed / Lapsed |