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US3920837A Expired / Lapsed US ⏱️ 0.0 years remaining

Method of treatment of calcium disorders using cyclohexane-hexacarboxylic acid

Assignee: Henkel AG and Co KGaA
•
Filing: 1974-08-20
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Granted: 1975-11-18
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Expires: 1994-08-20
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Abstract

Abstract A method for the treatment of diseases relating to the abnormal deposition or dissolution of difficultly soluble calcium salts in the body or mouths of warm-blooded animals which consists of administering orally, parenterally or topically to said warmblooded animals, a safe but effective amount of at least one pharmacologically acceptable cyclohexane-hexacarboxylic acid derivative selected from the group consisting of cyclohexane1,2,3,4,5,6-hexacarboxylic acid and water-soluble salts thereof.

Inventors

  • 👤 Manfred Schmidt-Dunker
  • 👤 Walter Ploger
  • 👤 Karl-Heinz Worms
  • 👤 Helmut Blum
  • 👤 Christian Gloxhuber

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-06 02:40
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K31/00; A61K31/185; A61K31/19; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/36; A61K8/362

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 68 words
A METHOD FOR ALLEVIATING CONDITIONS CAUSED BY THE ABNORMAL DEPOSITION OR DISSOLUTION OF DIFFICULTY SOLUBLE CALCIUM SALTS IN THE BODY OF WARM-BLOODED ANIMALS HAVING SAID CONDITIONS WHICH CONSISTS OF ADMINISTERING ORALLY OR PARENTERALLY TO SAID WARM-BLOODED ANIMALS, FROM 0.05 TO 500 MG/KG OF THE ANIMAL BODY WEIGHT OF AT LEAST ONE PHARMACOLOGICALLY ACCEPTABLE CYCLOHEXANE-HEXACARBOXYLIC ACID DERIVATIVE SELECTED FROM THE GROUP CONSISTING OF CYCLOHEXANE-1,2,3,4,5,6-HEXACARBOXYLIC ACID AND WATER-SOLUBLE SALTS THEREOF.
Claim 2
Independent Claim 68 words
A METHOD FOR ALLEVIATING CONDITIONS CAUSED BY THE ABNORMAL DEPOSITION OR DISSOLUTION OF DIFFICULTY SOLUBLE CALCIUM SALTS IN THE BODY OF WARM-BLOODED ANIMALS HAVING SAID CONDITIONS WHICH CONSISTS OF ADMINISTERING ORALLY OR PARENTERALLY TO SAID WARM-BLOODED ANIMALS, FROM 0.05 TO 500 MG/KG OF THE ANIMAL BODY WEIGHT OF AT LEAST ONE PHARMACOLOGICALLY ACCEPTABLE CYCLOHEXANE-HEXACARBOXYLIC ACID DERIVATIVE SELECTED FROM THE GROUP CONSISTING OF CYCLOHEXANE-1,2,3,4,5,6-HEXACARBOXYLIC ACID AND WATER-SOLUBLE SALTS THEREOF.
Claim 3
Dependent Claim 47 words
A composition for oral hygiene useful for the removal of tartar consisting essentially of from 0.01% to 5% by weight of at least one cyclohexane-hexacarboxylic acid derivative selected from the group consisting of cyclohexane-1,2,3,4,5,6-hexacarboxylic acid and its alkali metal salts, in admixture with an orally acceptable excipient.
Claim 4
Dependent Claim 47 words
A composition for oral hygiene useful for the removal of tartar consisting essentially of from 0.01% to 5% by weight of at least one cyclohexane-hexacarboxylic acid derivative selected from the group consisting of cyclohexane-1,2,3,4,5,6-hexacarboxylic acid and its alkali metal salts, in admixture with an orally acceptable excipient.
Claim 5
Independent Claim 61 words
A method for alleviating conditions caused by the deposition of difficultly soluble calcium salts on the teeth of warm-blooded animals having said conditions which consists of topically administering to the teeth of said warm-blooded animals, a safe but effective amount of at least one pharmacologically acceptable cyclohexane-hexacarboxylic acid derivative selected from the group consisting of cyclohexane-1,2,3,4,5,6-hexacarboxylic acid and water-soluble salts thereof.
Claim 6
Independent Claim 61 words
A method for alleviating conditions caused by the deposition of difficultly soluble calcium salts on the teeth of warm-blooded animals having said conditions which consists of topically administering to the teeth of said warm-blooded animals, a safe but effective amount of at least one pharmacologically acceptable cyclohexane-hexacarboxylic acid derivative selected from the group consisting of cyclohexane-1,2,3,4,5,6-hexacarboxylic acid and water-soluble salts thereof.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-11-17 1979-05-19 1979-11-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-11-17 1983-05-19 1983-11-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-11-17 1987-05-19 1987-11-18 $7700.00 Window Closed / Lapsed

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