US3919206A
Expired / Lapsed
US
⏱️ 0.0 years remaining
7-(Halomethylaryl)acetamidocephalosporin derivatives
Assignee: Yeda Research and Development Co Ltd
•
Filing: 1973-09-25
•
Granted: 1975-11-11
•
Expires: 1993-09-25
Abstract
Abstract Novel 7-(halomethylaryl)acetamidocephalosporin derivatives useful as antibiotic agents.
Inventors
- 👤 Abraham Patchornik
- 👤 Fortuna Haviv
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 10:08
CPC Classifications
C; C07; C07D; C07D333/00; C07D333/02; C07D333/04; C07D333/06; C07D333/24; C07C; C07C57/00; C07C57/52; C07C57/58; C07C57/64; C07C57/76; C07C59/00; C07C59/40; C07C59/58; C07C59/64; C07C59/66; C07C59/68; C07C59/70
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 2
Dependent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 3
Dependent Claim
9 words
A compound of claim 1 wherein Aryl is 2-thienyl.
Claim 4
Dependent Claim
13 words
A compund of claim 2 wherein W is selected from hydrogen or methyl.
Claim 5
Dependent Claim
10 words
A compound of claim 3 wherein Z is a bond.
Claim 6
Dependent Claim
9 words
A compound of claim 1 wherein Aryl is phenyl.
Claim 7
Dependent Claim
15 words
A compound of claim 5 wherein W is selected from hydrogen, methyl, amino or hydroxy.
Claim 8
Dependent Claim
10 words
A compound of claim 6 wherein Z is a bond.
Claim 9
Dependent Claim
14 words
A compound of claim 7 wherein Y is selected from hydrogen or lower alkoxy.
Claim 10
Dependent Claim
16 words
A compound of claim 8 which is 3-((acetyloxy)-methyl)-7-((2-(4-(chloromethyl)phenyl)acetyl)amino)-8-oxo-5 -thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid or a pharmaceutically acceptable salt thereof.
Claim 11
Dependent Claim
16 words
A compound of claim 8 which is 7-((2-(4-(chloromethyl)phenyl)acetyl)amino)-3-methyl-8-oxo-5-thia-1 -azabicyclo(4.2.0.)oct-2-ene-2-carboxylic acid or a pharmaceutically acceptable salt thereof.
Claim 12
Dependent Claim
16 words
A compound of claim 8 which is 7-((2-(2-bromomethyl)phenyl)acetyl)amino)-3-methyl-8-oxo-5-thia-1 -azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid or a pharmaceutically acceptable salt thereof.
Claim 13
Dependent Claim
16 words
A compound of claim 8 which is 3-((acetyloxy)-methyl)-7-((2-(2-(chloromethyl)-4-methoxyphenyl)-2 -hydroxyacetyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid or a pharmaceutically acceptable salt thereof.
Claim 14
Dependent Claim
16 words
A compound of claim 8 which is 7-((2-(2-(chloromethyl)-4-methoxyphenyl)-2-hydroxyacetyl)amino)-3-methyl-8 -oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid or a pharmcaeutically acceptable salt thereof.
Claim 15
Dependent Claim
11 words
A compound of claim 6 wherein Z is oxygen or sulfur.
Claim 16
Dependent Claim
14 words
A compound of claim 14 wherein Y is selected from hydrogen or lower alkoxy.
Claim 17
Dependent Claim
15 words
A compound of claim 1 which is 3-((acetyloxy)-methyl-7-((2-(2,4-bis(chloromethyl)phenyl)acetyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid or a pharmaceutically acceptable salt thereof.
Claim 18
Dependent Claim
16 words
A compound of claim 15 which is 3-((acetyloxy)methyl)-7-((2-(2,4-bis(chloromethyl)phenoxy)acetyl)amino)-8 -oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid or a pharmaceutically acceptable salt thereof.
References Cited (Backward Citations)
US3487074A
Cited
US3814754A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-11-10 | 1979-05-12 | 1979-11-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-11-10 | 1983-05-12 | 1983-11-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-11-10 | 1987-05-12 | 1987-11-11 | $7700.00 | Window Closed / Lapsed |