US3917668A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Prostanoic acid intermediates
Assignee: Wyeth LLC
•
Filing: 1973-04-16
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Granted: 1975-11-04
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Expires: 1993-04-16
Abstract
Abstract 15- And/or 16-alkyl derivatives of 9,15-dioxygenated prost-13enoic, prosta-4,13-dienoic and prosta-5,13-dienoic acid, lower alkyl esters thereof and homologs thereof, as well as a process for preparing these derivatives are disclosed. The compounds possess hypotensive, anti-hypertensive, bronchospasmolytic, gastric acid secretion inhibiting, abortifacient, estrus synchronizing and ovulation regulating properties. The compounds also inhibit the aggregation of platelets and promote the disaggregation of aggregated platelets. Methods for their use are also disclosed.
Inventors
- 👤 Nedumparambil A Abraham
- 👤 Jehan F Bagli
- 👤 Tibor Bogri
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 22:57
CPC Classifications
C; C07; C07F; C07F9/00; C07F9/02; C07F9/28; C07F9/54; C07F9/5407; C07C; C07C405/00; C07F9/38; C07F9/40; C07F9/4003; C07F9/4006; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
6 words
A COMPOUND OF THE FORMULA 6
Claim 2
Dependent Claim
6 words
A COMPOUND OF THE FORMULA 6
Claim 3
Dependent Claim
9 words
Dimethyl cis, trans-3-(6-carbomethoxy-2-hexenyl)-4-(3-hydroxy-4,4-dimethyl-1-octenyl)-2 -oxo-1,3-cyclopentanedicarboxylate, as claimed in claim 1.
Claim 4
Dependent Claim
9 words
Diethyl cis, trans-3-(6-carboethoxy-2-hexenyl)4-(3-hydroxy-3-methyl-1-octenyl)-2-oxo-1,3 -cyclopentanedicarboxylate, as claimed in claim 1.
Claim 5
Dependent Claim
9 words
Diethyl cis, trans-3-(6-carboethoxy-2-hexenyl)-4-)3-((tetrahydropyran-2-yl)oxy)-3-methyl -1-octenyl)-2-oxo-1,3-cyclopentanedicarboxylate, as claimed in claim 1.
Claim 6
Dependent Claim
8 words
Diethyl trans-3-(6-carboethoxyhexanyl)-4-(3-hydroxy-3-methyl-1-octenyl)-2-oxo-1,3 -cyclopentanedicarboxylate, as claimed in claim 1.
Claim 7
Dependent Claim
8 words
Diethyl trans-3-(6-carboethoxyhexanyl-4-(3-((tetrahydropyran-2-yl)oxy)-3-methyl-1 -octenyl)-2-oxo-1,3-cyclopentanedicarboxylate, as claimed in claim 1.
Claim 8
Dependent Claim
8 words
Diethyl cis, trans-3-(6-carboethoxy-2-hexenyl)-4-(3-hydroxy-4-methyl-1-octenyl)-2-oxo-1,3-cyclopentanedicarboxylate, as claimed in claim 1.
Claim 9
Dependent Claim
8 words
Diethyl cis, trans-3-(6-carboethoxy-3-hexenyl)-4-(3-hydroxy-3-methyl-1-octenyl)-2-oxo-1,3-cyclopentanedicarboxylate, as claimed in claim 1.
Claim 10
Dependent Claim
24 words
The compound of claim 1 wherein R7 is hydrogen or a protecting group selected from the group consisting of tetrahydropyran-2-yl, trimethylsilyl, dimethylisopropylsilyl, and tert-butyl.
References Cited (Backward Citations)
US3736319A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-11-03 | 1979-05-05 | 1979-11-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-11-03 | 1983-05-05 | 1983-11-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-11-03 | 1987-05-05 | 1987-11-04 | $7700.00 | Window Closed / Lapsed |