US3904604A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1-amino substituted 1-cycloalkane derivatives of 6-aminopenicillanic acid
Assignee: ER Squibb and Sons LLC
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Filing: 1972-08-21
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Granted: 1975-09-09
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Expires: 1992-08-21
Abstract
Abstract Disclosed herein are novel compounds of the formula and wherein m is 0, 1 or 2; R is alkyl of from 1 to 7 carbon atoms, hydroxy or halogen; n is 0, 1, 2 or 3; R1 is phenyl, naphthyl, substituted phenyl or naphthyl wherein the substituent is halogen, hydroxy, or alkyl, alkoxy or acyl, each of from 1 to 4 carbon atoms, or amido; and Z is hydrogen, alkyl of from 1 to 7 carbon atoms or a salt forming ion. These compounds, prepared by condensing a Schiff''s base of a 1-amino substituted 1-cycloalkane carboxylic acid with 6-APA, are useful as antibacterial agents.
Inventors
- 👤 Bong Kuk Lee
- 👤 Saul Lewis Neidleman
- 👤 Dewey D Y Ryu
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 13:29
CPC Classifications
C; C07; C07D; C07D499/00
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 2
Dependent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 3
Dependent Claim
10 words
A compound of claim 1 wherein Q is -N CHR1.
Claim 4
Dependent Claim
42 words
A compound of claim 2 wherein R1 is substituted phenyl or substituted naphthyl the substituent being halogen, hydroxy, amido, alkyl of from 1 to 4 carbons, alkoxy of from 1 to 4 carbons or acyl of from 1 to 4 carbon atoms.
Claim 5
Dependent Claim
13 words
A compound of claim 5 wherein the substituent is in the ortho position.
Claim 6
Dependent Claim
17 words
A compound of claim 1 having the name 6-((1-(((2-hydroxy-1-naphthyl) methylene) amino) cyclopent-1-yl)-carboxamido) pencillanic acid, sodium, salt, hydrate.
Claim 7
Dependent Claim
12 words
A compound of claim 1 having the name 6-((1-(((2-hydroxy-1-naphthyl)methyl)amino)cyclopent-1-yl)carboxamide) -penicillanic acid, hydrate.
References Cited (Backward Citations)
US3351587A
Cited
US3594366A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-09-08 | 1979-03-10 | 1979-09-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-09-08 | 1983-03-10 | 1983-09-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-09-08 | 1987-03-10 | 1987-09-09 | $7700.00 | Window Closed / Lapsed |