US3904599A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cardenolide-3-(2'-desoxy-glycosides)+0 and process for their manufacture
Assignee: Hoechst AG
•
Filing: 1973-07-26
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Granted: 1975-09-09
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Expires: 1993-07-26
Abstract
Abstract Cardenolide-3-(2''-desoxy-glycosides) of the formula useful in the treatment of cardiac and circulatory diseases, wherein R1 is a steroid of the 3-hydroxy-cardenolide series, R2 is hydrogen, lower aliphatic acyl, or aromatic acyl, and R3 is hydrogen, methyl, or -CH2OR2.
Inventors
- 👤 Ulrich Stache
- 👤 Werner Fritsch
- 👤 Werner Haede
- 👤 Kurt Radscheit
- 👤 Ernst Lindner
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 21:22
CPC Classifications
C; C07; C07J; C07J19/00; C07J19/005
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
3 words
A CARDENOLIDE-3- 2''-DESOXYY-GLYCOSIDE
Claim 2
Dependent Claim
3 words
A CARDENOLIDE-3- 2''-DESOXYY-GLYCOSIDE
Claim 3
Dependent Claim
11 words
A compound as in claim 1 which is digitoxigenin-3- Alpha -(L-digitoxoside).
Claim 4
Dependent Claim
13 words
A compound as in claim 1 which is 19-carboxymethyleneperiplogenin-5 Beta -lactone-3- Alpha -(L-digitoxoside).
Claim 5
Dependent Claim
11 words
A compound as in claim 1 which is K-strophanthidin3- Alpha -(L-digitoxoside).
Claim 6
Independent Claim
9 words
A method for making a cardenolide-3-(2''-desoxyglycoside) of the formula
Claim 7
Independent Claim
9 words
A method for making a cardenolide-3-(2''-desoxyglycoside) of the formula
Claim 8
Dependent Claim
13 words
A method as in claim 5 wherein said Raney-nickel catalyst is noble-metal activated.
Claim 9
Dependent Claim
32 words
A method as in claim 5 wherein R2 is benzoyl or alkanoyl having 1 to 4 carbon atoms and wherein R2 is removed from such a cardenolide-3-(2''-desoxy-glycoside) by hydrolysis under alkaline conditions.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-09-08 | 1979-03-10 | 1979-09-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-09-08 | 1983-03-10 | 1983-09-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-09-08 | 1987-03-10 | 1987-09-09 | $7700.00 | Window Closed / Lapsed |