US3903266A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Compositions and methods for disaggregating blood cells
Assignee: Individual
•
Filing: 1974-09-24
•
Granted: 1975-09-02
•
Expires: 1994-09-24
Abstract
Abstract Methoxylated flavonoids having at least two methoxyl radicals or substituents exhibit powerful anti-adhesive effects on blood cells in vivo and in vitro. When such flavonoids are combined with an anticoagulant, greater protection against thrombi formation is provided than when either is used without the other.
Inventors
- 👤 Ralph C Robbins
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 16:33
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/715; A61K31/33; A61K31/335; A61K31/35
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
22 words
A COMPOSITION FOR DISAGGREGATING BLOOD CELLS AND INHIBITING BLOOD COAGULATION COMPRISING A FLAVONOID HAVING AT LEAST TWO METHOXYL SUBSTITUENTS AND AN ANTICOAGULANT.
Claim 2
Dependent Claim
22 words
A COMPOSITION FOR DISAGGREGATING BLOOD CELLS AND INHIBITING BLOOD COAGULATION COMPRISING A FLAVONOID HAVING AT LEAST TWO METHOXYL SUBSTITUENTS AND AN ANTICOAGULANT.
Claim 3
Dependent Claim
20 words
The composition as defined in claim 1 wherein said flavonoid is 3'', 4'', 5, 6, 7, 8 - hexamethoxyflavone (Nobiletin).
Claim 4
Dependent Claim
12 words
The composition as defined in claim 1 wherein said anticoagulant is Heparin.
Claim 5
Dependent Claim
25 words
The composition as defined in claim 1 wherein said flavonoid is 3'', 4'', 5, 6, 7, 8 - hexamethoxyflavone (Nobiletin) and said anticoagulant is Heparin.
Claim 6
Independent Claim
26 words
A method of disaggregating blood cells and inhibiting blood coagulation comprising infusion into the bloodstream a flavonoid having at least two methoxyl substituents and an anticoagulant.
Claim 7
Independent Claim
26 words
A method of disaggregating blood cells and inhibiting blood coagulation comprising infusion into the bloodstream a flavonoid having at least two methoxyl substituents and an anticoagulant.
Claim 8
Dependent Claim
20 words
The method as defined in claim 5 wherein said flavonoid is 3'', 4'', 5, 6, 7, 8 - hexamethoxyflavone (Nobiletin).
Claim 9
Dependent Claim
12 words
The method as defined in claim 5 wherein said anticoagulant is Heparin.
Claim 10
Dependent Claim
25 words
The method as defined in claim 5 wherein said flavonoid is 3'', 4'', 5, 6, 7, 8 - hexamethoxyflavone (Nobiletin) and said anticoagulant is Heparin.
References Cited (Backward Citations)
US2543674A
Cited
US3247063A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-09-01 | 1979-03-03 | 1979-09-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-09-01 | 1983-03-03 | 1983-09-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-09-01 | 1987-03-03 | 1987-09-02 | $7700.00 | Window Closed / Lapsed |