US3899496A
Expired / Lapsed
US
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Production of 1-aminoalkane-1,1-diphosphonic acids
Assignee: Henkel AG and Co KGaA
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Filing: 1973-11-21
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Granted: 1975-08-12
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Expires: 1993-11-21
Abstract
Abstract The present invention provides a process for the production of 1-aminoalkane-1,1-diphosphonic acids of the formula IN WHICH R represents a hydrogen atom, an alkyl residue with 1 to 12 carbon atoms, a phenyl group, a cyclohexyl group, a phenylalkyl group with 7-12 carbon atoms, a piperidinyl group, a carboxyalkyl group with 2-12 carbon atoms, or a carbalkoxy alkyl group with 3-12 carbon atoms; and in which X represents an NH2 group, a piperidino group, a morpholino group or a NR1R2 group, wherein R1 and R2 represent alkyl residues with 1 to 4 carbon atoms, comprising reacting a corresponding compound of the formula RCCl2X or RCBr2X, such as the corresponding carboxylic acid amide dichlorides or dibromides, with phosphorous acid.
Inventors
- 👤 Norbert Schindler
- 👤 Walter Ploger
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 02:29
CPC Classifications
C; C07; C07F; C07F9/00; C07F9/02; C07F9/28; C07F9/38; C07F9/3804; C07F9/3839; C07F9/3873
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
11 words
A PROCESS FOR THE PRODUCTION OF 1,1-DIPHOSPHONIC ACIDS OF THE FORMULA
Claim 2
Dependent Claim
11 words
A PROCESS FOR THE PRODUCTION OF 1,1-DIPHOSPHONIC ACIDS OF THE FORMULA
Claim 3
Dependent Claim
23 words
The process of claim 1 in which said amide dihalide is reacted with phosphorous acid in the molar ratio of 1:2 to 1:0.5.
Claim 4
Dependent Claim
21 words
The process of claim 2 in which said amide dihalide is reacted with phosphorous acid in the molar ratio of 1:1.
Claim 5
Dependent Claim
11 words
A process for the production of 1,1-diphosphonic acids of the formula
Claim 6
Dependent Claim
11 words
A process for the production of 1,1-diphosphonic acids of the formula
Claim 7
Dependent Claim
22 words
The process of claim 4 wherein said inert solvent is selected from the group consisting of carbon tetrachloride, dimethylformamide, and diethyl ether.
Claim 8
Dependent Claim
23 words
The process of claim 4 in which said amide dihalide is reacted with phosphorous acid in the molar ratio of 1:2 to 1:0.5.
Claim 9
Dependent Claim
21 words
The process of claim 5 in which said amide dihalide is reacted with phosphorous acid in the molar ratio of 1:1.
Claim 10
Dependent Claim
42 words
A process for the production of N,N-dimethylaminomethane-1,1-diphosphonic acid consisting of reacting dimethylformamide suspended in carbon tetrachloride, with phosphorus pentachloride, reacting the resultant suspension consisting of carbon tetrachloride, phosphorus oxychloride and the corresponding amide dichloride, with phosphorous acid; and recovering said 1,1-diphosphonic acid.
Claim 11
Dependent Claim
42 words
A process for the production of N,N-dimethylaminomethane-1,1-diphosphonic acid consisting of reacting dimethylformamide suspended in carbon tetrachloride, with phosphorus pentachloride, reacting the resultant suspension consisting of carbon tetrachloride, phosphorus oxychloride and the corresponding amide dichloride, with phosphorous acid; and recovering said 1,1-diphosphonic acid.
Claim 12
Dependent Claim
23 words
The process of claim 8 wherein said amide dichloride and said phosphorous acid are reacted in a molar ratio of 1:2 to 1:0.5.
Claim 13
Dependent Claim
11 words
The process of claim 9 wherein said molar ratio is 1:1.
Claim 14
Dependent Claim
31 words
A process for the production of 1-piperidinomethane-1,1-diphosphonic acid consisting of reacting piperidinoformamide suspended in carbon tetrachloride, with phosphorus pentachloride, reacting the resultant suspension with phosphorous acid; and recovering said 1-piperidinomethane-1,1-diphosphonic acid.
Claim 15
Dependent Claim
31 words
A process for the production of 1-piperidinomethane-1,1-diphosphonic acid consisting of reacting piperidinoformamide suspended in carbon tetrachloride, with phosphorus pentachloride, reacting the resultant suspension with phosphorous acid; and recovering said 1-piperidinomethane-1,1-diphosphonic acid.
References Cited (Backward Citations)
US2900408A
Cited
US3288846A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-08-11 | 1979-02-10 | 1979-08-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-08-11 | 1983-02-10 | 1983-08-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-08-11 | 1987-02-10 | 1987-08-12 | $7700.00 | Window Closed / Lapsed |