US3898335A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical compositions and methods of inhibiting gastric acid secretion
Assignee: GlaxoSmithKline LLC
•
Filing: 1974-10-15
•
Granted: 1975-08-05
•
Expires: 1994-10-15
Abstract
Abstract Pharmaceutical compositions and methods of inhibiting gastric acid secretion by administering 2-alkoxy(and 2-amino)-3-amino-2heterocyclic-2-thiopropanamides.
Inventors
- 👤 Bernard Loev
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 19:34
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/30; C07D207/32
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
31 words
A PHARMACEUTICAL COMPOSITION HAVING GASTRIC ACID SECRETION INHIBITORY ACTIVITY, IN DOSAGE UNIT FORM, COMPRISING A PHARMACEUTICAL CARRIER AND A GASTERIC ACID SECRETION INHIBITING AMOUNT OF A THIOAMIDE COMPOUND OF THE FORMULA:
Claim 2
Dependent Claim
31 words
A PHARMACEUTICAL COMPOSITION HAVING GASTRIC ACID SECRETION INHIBITORY ACTIVITY, IN DOSAGE UNIT FORM, COMPRISING A PHARMACEUTICAL CARRIER AND A GASTERIC ACID SECRETION INHIBITING AMOUNT OF A THIOAMIDE COMPOUND OF THE FORMULA:
Claim 3
Dependent Claim
11 words
The pharmaceutical composition of claim 1 in which R1 is 2-pyridyl.
Claim 4
Dependent Claim
11 words
The pharmaceutical composition of claim 1 in which R3 is morpholino.
Claim 5
Dependent Claim
12 words
The pharmaceutical composition of claim 1 in which R2 is lower alkoxy.
Claim 6
Dependent Claim
25 words
The pharmaceutical composition of claim 1 in which R1 is 2-pyridyl, R2 is methoxy, R3 is morpholino and R4 is NH-methyl, NH-ethyl, NH-(CH2)n-cycloalkyl or NH-allyl.
Claim 7
Dependent Claim
13 words
The pharmaceutical composition of claim 1 in which the thioamide compound is 2-methoxy-N-methyl-3-morpholino-2-(2-pyridyl)thiopropanamide.
Claim 8
Dependent Claim
25 words
The pharmaceutical composition of claim 1 in which the thioamide compound is present in an amount of from about 10 mg. to about 500 mg.
Claim 9
Independent Claim
32 words
A method of inhibiting gastric acid secretion which comprises administering internally to an animal in need of said treatment an effective gastric acid inhibiting amount of a thioamide compound of the formula:
Claim 10
Independent Claim
32 words
A method of inhibiting gastric acid secretion which comprises administering internally to an animal in need of said treatment an effective gastric acid inhibiting amount of a thioamide compound of the formula:
Claim 11
Dependent Claim
10 words
The method of claim 8 in which R1 is 2-pyridyl.
Claim 12
Dependent Claim
10 words
The method of claim 8 in which R3 is morpholino.
Claim 13
Dependent Claim
12 words
The method of claim 8 in which the thioamide compound is 2-methoxy-N-methyl-3-morpholino-2-(2-pyridyl)-thiopropanamide.
Claim 14
Dependent Claim
25 words
The method of claim 8 in which the thioamide compound is administered in a daily dosage of from about 10 mg. to about 2 g.
References Cited (Backward Citations)
US3686190A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-08-04 | 1979-02-03 | 1979-08-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-08-04 | 1983-02-03 | 1983-08-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-08-04 | 1987-02-03 | 1987-08-05 | $7700.00 | Window Closed / Lapsed |