US3884916A
Expired / Lapsed
US
⏱️ 0.0 years remaining
2,2-Diaryl-4-(4-aryl-4-hydroxy-piperidino)-butyramides
Assignee: Janssen Pharmaceutica NV
•
Filing: 1972-12-07
•
Granted: 1975-05-20
•
Expires: 1992-12-07
Abstract
Abstract Compounds of the class of 2,2-diaryl-4-(4''-aryl-4''hydroxypiperidino)butyramides wherein said aryl and said amide functions are variously defined groups, said butyramides having anti-diarrheal and analgesic activities; also included are novel intermediates used in the synthesis of said butyramides.
Inventors
- 👤 Paul Adriaan Jan Janssen
- 👤 Carlos Jan Ernest J Niemegeers
- 👤 Raymond Antoine Stokbroekx
- 👤 Jan Vandenberk
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 00:24
CPC Classifications
C; C07; C07D; C07D211/00; C07D211/04; C07D211/68; C07D211/72; C07D211/74; C07D211/06; C07D211/36; C07D211/40; C07D211/44; C07D211/52; C07D211/78
Claims Analysis
Total Claims: 40
Claim 1
Independent Claim
6 words
3,3-DIARYL-TETRAHYDRO-2-FURYLIDENE AMMONIUM SALTS HAVING THE FORMULA:
Claim 2
Dependent Claim
6 words
3,3-DIARYL-TETRAHYDRO-2-FURYLIDENE AMMONIUM SALTS HAVING THE FORMULA:
Claim 3
Dependent Claim
3 words
1-(tetrahydro-3,3-diphenyl-2-furylidene) pyrrolidinium bromide.
Claim 4
Dependent Claim
3 words
1-(tetrahydro-3,3-diphenyl-2-furylidene) pyrrolidinium bromide.
Claim 5
Dependent Claim
3 words
1-(tetrahydro-3,3-diphenyl-2-furylidene) piperidinium bromide.
Claim 6
Dependent Claim
3 words
1-(tetrahydro-3,3-diphenyl-2-furylidene) piperidinium bromide.
Claim 7
Dependent Claim
3 words
4-(tetrahydro-3,3-diphenyl-2-furylidene) morpholinium bromide.
Claim 8
Dependent Claim
3 words
4-(tetrahydro-3,3-diphenyl-2-furylidene) morpholinium bromide.
Claim 9
Dependent Claim
4 words
Dimethyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 10
Dependent Claim
4 words
Dimethyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 11
Dependent Claim
4 words
Diethyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 12
Dependent Claim
4 words
Diethyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 13
Dependent Claim
4 words
Dimethyl (tetrahydro-5-methyl-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 14
Dependent Claim
4 words
Dimethyl (tetrahydro-5-methyl-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 15
Dependent Claim
3 words
1-(tetrahydro-5-methyl-3,3-diphenyl-2-furylidene) pyrrolidinium bromide.
Claim 16
Dependent Claim
3 words
1-(tetrahydro-5-methyl-3,3-diphenyl-2-furylidene) pyrrolidinium bromide.
Claim 17
Dependent Claim
4 words
Dipropyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 18
Dependent Claim
4 words
Dipropyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 19
Dependent Claim
4 words
Dibutyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 20
Dependent Claim
4 words
Dibutyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 21
Dependent Claim
3 words
2,6-dimethyl-4-(tetrahydro-3,3-diphenyl-2-furylidene) morpholinium bromide.
Claim 22
Dependent Claim
3 words
2,6-dimethyl-4-(tetrahydro-3,3-diphenyl-2-furylidene) morpholinium bromide.
Claim 23
Dependent Claim
3 words
4-methyl-1-(tetrahydro-3,3-diphenyl-2-furylidene) piperidinium bromide.
Claim 24
Dependent Claim
3 words
4-methyl-1-(tetrahydro-3,3-diphenyl-2-furylidene) piperidinium bromide.
Claim 25
Dependent Claim
4 words
Ethylmethyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 26
Dependent Claim
4 words
Ethylmethyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 27
Dependent Claim
3 words
3-methyl-1-(tetrahydro-3,3-diphenyl-2-furylidiene) piperidinium bromide.
Claim 28
Dependent Claim
3 words
3-methyl-1-(tetrahydro-3,3-diphenyl-2-furylidiene) piperidinium bromide.
Claim 29
Dependent Claim
4 words
Benzylmethyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 30
Dependent Claim
4 words
Benzylmethyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 31
Dependent Claim
4 words
Diallyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 32
Dependent Claim
4 words
Diallyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 33
Dependent Claim
4 words
Methylpropyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 34
Dependent Claim
4 words
Methylpropyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 35
Dependent Claim
4 words
Methylisopropyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 36
Dependent Claim
4 words
Methylisopropyl (tetrahydro-3,3-diphenyl-2-furylidene) ammonium bromide.
Claim 37
Dependent Claim
2 words
(3,3-bis(p-fluorophenyl)tetrahydro-2-furylidene)dimethylammonium bromide.
Claim 38
Dependent Claim
2 words
(3,3-bis(p-fluorophenyl)tetrahydro-2-furylidene)dimethylammonium bromide.
Claim 39
Dependent Claim
6 words
3,3-Diphenyl-tetrahydro-2-furylidene ammonium salts having the formula:
Claim 40
Dependent Claim
6 words
3,3-Diphenyl-tetrahydro-2-furylidene ammonium salts having the formula:
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-05-19 | 1978-11-18 | 1979-05-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-05-19 | 1982-11-18 | 1983-05-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-05-19 | 1986-11-18 | 1987-05-20 | $7700.00 | Window Closed / Lapsed |