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US3882026A Expired / Lapsed US ⏱️ 0.0 years remaining

Hydrophobic filter device for medical liquids

Assignee: Kendall Mcgraw Laboratories Inc
•
Filing: 1972-08-14
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Granted: 1975-05-06
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Expires: 1992-08-14
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Abstract

Abstract A device for filtering a parenteral solution immediately before it is infused into a patient''s vein. The device has a hollow housing containing a ''''depth'''' filter membrane of nonfibrous hydrophobic material having randomly connected stacked passages of from 10 to 40 micron size through the filter. After the filter membrane has had one surface in contact with the parenteral solution for a period of 15 to 60 seconds while passing only a minute amount of liquid it is then manually tapped to send a shock wave through the filter. This shock wave unexpectedly causes the hydrophobic filter to freely pass liquid and filter out more than 90 percent of all particulate matter of 5 micron size and larger from the parenteral solution. The large pore hydrophobic filter membrane can perform these filtering efficiencies with a very small, thin disc-shaped membrane of approximately one-fourth inch effective diameter.

Inventors

  • 👤 Charles J Mcphee

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 12:00
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/165; A61M2005/1657

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 362 words
A LIQUID FILTER ASSEMBLY FOR FILTERING AT PARENTERAL SOLUTION HEAD-PRESSURES IMMEDIATELY AT THE SITE FOR ADMINISTERING THE SOLUTION TO A PATIENT AT FLOW RATES USED IN CONVENTIONAL PARENTERAL THERAPY COMRPISING: AN ELONGATED HOLLOW HOUSING HAVING A LIQUID INLET OPENING; A RIGID TUBULAR INLET ADAPTER AT ONE END SORROUNDING THE INLET OPENING FOR CONNECTING THE HOUSING TO A TUBULAR ADMISISTRATION SET LEADING FROM AN ELEVATED PARENTERAL LIQUID SOURCE; SAID HOUSING HAVING A LIQUID OUTLET OPENING SPACED FROM THE INLWT OPENING; A RIGID TUBLAR OUTLET NEEDLE ADAPTER IN AXIAL ALIGNEMENT WITH THE INLWT ADAPTER AND SURROUNDING THE OUTLET, SAID NEEDLY OUTLET ADAPTER INCLUDING A TAPERED ANNULAR SURFACE FOR WEDGINGLY CONNECTING TO A TAPERED ANNULAR SURFACE HUB OF A VENOUS NEDDLE FOR DISPENSING FILTERED LIQUID IMMEDIATELY AT THE NEEDLE SITE OF A PATEINTS, ANTOMY; AND A "DEPTH" FILTER MEMBRANE OF HYDROPHOBIC HOMOGENOUS MATERIAL WITH RANDOMLY COMMUNICATING INTERCONNECTED AXIALLY STACKET PASSAGES OF FROM 10 TO 40 MICRON SIZE AND COMMUNICATING BETWEEN SAID LIQUID INLET OPENING AND LIQUID OUTLET OPENING, SAID FILTER MEMBRANE FITTING TRANVERSELY INSIDE THE HOUSING AND PERIPHERALLY SEALED THERETO BETWEEN THE LIQUID INLET AND OUTLET OPENINGS WHEREBY ALL LIQUID PASSING THROUGH THE ASSEMBLY MUST PASS THROUGH THE STACKED PASSAGES, SAID HOUSING INCLUDES AT LEAST ONE SUPPORT PRONG ON A DOWNSTREAM SIDE OF THE FILTER MEMBRANE, SAID SUPPORT PRONG HAVING A ROUNDED CONTACT SURFACE TERMINALLY ENGAGING A CENTRAL PORTION OF THE MEMBRANE, SAID MEMBRANE BEING RELATIVELY FLEXIBLE AND THE PRONG ABSORBING SHOCK OF PRESSURE SURGES TO PROTECT IT FROM RUPTURING UNDER A HIGH PRESSURE SURGE, SAID ROUNDED PRONG CONTACT SURFACE COVERING LESS THAN 5 PER CENT OF THE EFFECTIVE FILTER AREA OF THE FILTER MEMBRANE WHEN IN CONTACT THEREWITH, SAID FILTER MEMBRANE BEING A POROUS NORMALLY HYDROPHOBIC STRUCTURE IMPERVIOUS TO AT LEAST 90 PER CENT OF ALL PARTICULATE MATTER OF 5 MICRON SIZE AND GREATER FROM A PARENTERAL SOLUTION PASSING THROUGH ITS RANDOMLY INTERCONNECTED 10 TO 40 MICRON SIZE PASSAGES, THE FILTER MEMBRANE BEING FROM 0.003 AND 0.016 INCHES THICK AND HAVING AN EFFECTIVE FILTER AREA EQUIVALENT TO A 0.250 INCHES DIAMETER DISC, THE HOUSING INCLUDING A CENTRAL SECTION WHICH CONTAINS SAID FILTER MEMBRANE, SAID CENTRAL SECTION COMPRISING ESSENTIALLY AN AXIAL PROJECTION BETWEEN SAID ADAPTERS.
Claim 2
Dependent Claim 362 words
A LIQUID FILTER ASSEMBLY FOR FILTERING AT PARENTERAL SOLUTION HEAD-PRESSURES IMMEDIATELY AT THE SITE FOR ADMINISTERING THE SOLUTION TO A PATIENT AT FLOW RATES USED IN CONVENTIONAL PARENTERAL THERAPY COMRPISING: AN ELONGATED HOLLOW HOUSING HAVING A LIQUID INLET OPENING; A RIGID TUBULAR INLET ADAPTER AT ONE END SORROUNDING THE INLET OPENING FOR CONNECTING THE HOUSING TO A TUBULAR ADMISISTRATION SET LEADING FROM AN ELEVATED PARENTERAL LIQUID SOURCE; SAID HOUSING HAVING A LIQUID OUTLET OPENING SPACED FROM THE INLWT OPENING; A RIGID TUBLAR OUTLET NEEDLE ADAPTER IN AXIAL ALIGNEMENT WITH THE INLWT ADAPTER AND SURROUNDING THE OUTLET, SAID NEEDLY OUTLET ADAPTER INCLUDING A TAPERED ANNULAR SURFACE FOR WEDGINGLY CONNECTING TO A TAPERED ANNULAR SURFACE HUB OF A VENOUS NEDDLE FOR DISPENSING FILTERED LIQUID IMMEDIATELY AT THE NEEDLE SITE OF A PATEINTS, ANTOMY; AND A "DEPTH" FILTER MEMBRANE OF HYDROPHOBIC HOMOGENOUS MATERIAL WITH RANDOMLY COMMUNICATING INTERCONNECTED AXIALLY STACKET PASSAGES OF FROM 10 TO 40 MICRON SIZE AND COMMUNICATING BETWEEN SAID LIQUID INLET OPENING AND LIQUID OUTLET OPENING, SAID FILTER MEMBRANE FITTING TRANVERSELY INSIDE THE HOUSING AND PERIPHERALLY SEALED THERETO BETWEEN THE LIQUID INLET AND OUTLET OPENINGS WHEREBY ALL LIQUID PASSING THROUGH THE ASSEMBLY MUST PASS THROUGH THE STACKED PASSAGES, SAID HOUSING INCLUDES AT LEAST ONE SUPPORT PRONG ON A DOWNSTREAM SIDE OF THE FILTER MEMBRANE, SAID SUPPORT PRONG HAVING A ROUNDED CONTACT SURFACE TERMINALLY ENGAGING A CENTRAL PORTION OF THE MEMBRANE, SAID MEMBRANE BEING RELATIVELY FLEXIBLE AND THE PRONG ABSORBING SHOCK OF PRESSURE SURGES TO PROTECT IT FROM RUPTURING UNDER A HIGH PRESSURE SURGE, SAID ROUNDED PRONG CONTACT SURFACE COVERING LESS THAN 5 PER CENT OF THE EFFECTIVE FILTER AREA OF THE FILTER MEMBRANE WHEN IN CONTACT THEREWITH, SAID FILTER MEMBRANE BEING A POROUS NORMALLY HYDROPHOBIC STRUCTURE IMPERVIOUS TO AT LEAST 90 PER CENT OF ALL PARTICULATE MATTER OF 5 MICRON SIZE AND GREATER FROM A PARENTERAL SOLUTION PASSING THROUGH ITS RANDOMLY INTERCONNECTED 10 TO 40 MICRON SIZE PASSAGES, THE FILTER MEMBRANE BEING FROM 0.003 AND 0.016 INCHES THICK AND HAVING AN EFFECTIVE FILTER AREA EQUIVALENT TO A 0.250 INCHES DIAMETER DISC, THE HOUSING INCLUDING A CENTRAL SECTION WHICH CONTAINS SAID FILTER MEMBRANE, SAID CENTRAL SECTION COMPRISING ESSENTIALLY AN AXIAL PROJECTION BETWEEN SAID ADAPTERS.
Claim 3
Dependent Claim 27 words
The combination as set forth in claim 1 wherein the hydrophobic filter membrane comprises polytetrafluoroethylene and the randomly communicating passages are from 20 to 30 micron size.
Claim 4
Dependent Claim 45 words
The combination as set forth in claim 2 wherein the hydrophobic filter membrane comprises a plurality of hydrophobic membrane layers in face-to-face relationship, each membrane being of 0.003 to 0.008 inch thick and having interconnecting random communicating passages of from 20 to 30 micron size.
Claim 5
Dependent Claim 45 words
The combination as set forth in claim 1 wherein there are a series of round tipped support prongs surrounding the outlet of the housing, said support prongs blocking off less than 20 percent of the effective filtering area when in contact with the filter membrane.
Claim 6
Dependent Claim 68 words
The combination as set forth in claim 1 wherein the filter membrane is slightly flexible at the prong''s covered surface whereby a liquid pressure surge from an upstream side of the filter membrane will temporarily urge the membrane into more area contact between the prong and membrane, said membrane after the pressure surge, to rest on a smaller crowned area of the rounded contact surface of the prong.
Claim 7
Dependent Claim 91 words
The combination as set forth in claim 1 wherein the housing is formed of two hollow members, a first body member telescopically fitting within a second body member and permanently sealed together in a relationship which seals the filter membrane adjacent the housing outlet, said first hollow body member including a hydraulic pressure surface and wiper surface for hydraulically urging a bonding solvent through the peripheral passages of the filter membrane to the other hollow body and preventing parenteral solution from short circuiting aRound the peripheral edges of the filter membrane.
Claim 8
Dependent Claim 51 words
The combination as set forth in claim 6 wherein the hydraulic pressure surface includes a series of peripheral, axially extending grooves juxtaposed on one side of the filter membrane for retaining a bonding solvent therein and a series of land surfaces for forcing bonding solvent into passages of the filter membrane.
Claim 9
Dependent Claim 64 words
The combination as set forth in claim 1 wherein there are two filter membranes in the shape of discs each having a thickness of from 0.003 to 0.008 inch and are in face-to-face contact with each other, said filter membrane capable of filtering more than 95 percent of all particles of greater than 5 micron from a parenteral liquid passing through the filter membranes.

References Cited (Backward Citations)

US966963A Cited
US3157481A Cited
US3295684A Cited
US3471019A Cited
US3631654A Cited
US3650093A Cited
US3658183A Cited
US3753500A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-05-05 1978-11-04 1979-05-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-05-05 1982-11-04 1983-05-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-05-05 1986-11-04 1987-05-06 $7700.00 Window Closed / Lapsed

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