US3880891A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Substituted benzofurans
Assignee: GlaxoSmithKline LLC
•
Filing: 1973-09-21
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Granted: 1975-04-29
•
Expires: 1993-09-21
Abstract
Abstract The compounds of this invention are substituted benzofurans having pharmacological activity. In particular, these compounds have coronary vasodilator activity and are useful in the treatment of angina pectoris.
Inventors
- 👤 David T Hill
- 👤 Bernard Loev
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 14:10
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/77; C07D307/78; C07D307/79; C07D307/81; A; A61; A61P; A61P9/00; A61P9/08; A61P9/10; A61P9/12; C07C; C07C45/00; C07C45/61; C07C45/63; C07D307/80
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
5 words
A COMPOUND OF THE FORMULA:
Claim 2
Dependent Claim
5 words
A COMPOUND OF THE FORMULA:
Claim 3
Dependent Claim
50 words
A compound of claim 1 in which R2 is hydrogen, lower alkyl or phenyl(CH2)n where n is 0 or 1 and the phenyl moiety is optionally substituted with methyl, methoxy, trifluoromethyl or chloro, R5, R7 and R8 are hydrogen, R6 is hydrogen or methyl and R9 is NH(isopropyl) or NH(t-butyl).
Claim 4
Dependent Claim
27 words
A compound of claim 2 in which R1 is hydrogen or chloro in the 5-position, R4 is hydrogen or halogen, m is 1 and R6 is hydrogen.
Claim 5
Dependent Claim
12 words
A compound of claim 3 in which R1 is hydrogen, R3 is
Claim 6
Dependent Claim
9 words
A compound of claim 4 being the compound 2-n-butyl-3-(4''-(2-hydroxy-3-isopropylamino)propoxybenzoyl)-benzofuran.
Claim 7
Dependent Claim
10 words
A compound of claim 4 being the compound 2-n-butyl-3-(3''-chloro-4''-(2-hydroxy-3 -isopropylamino)propoxybenzoyl)benzofuran.
Claim 8
Dependent Claim
10 words
A compound of claim 4 being the compound 2-n-butyl-3-(4''-chloro-2''-(2-hydroxy-3 -isopropylamino)propoxybenzoyl)benzofuran.
Claim 9
Dependent Claim
10 words
A compound of claim 4 being the compound 2-(4''-chlorobenzyl)-3-(4''-(2-hydroxy-3 -isopropylamino)propoxybenzoyl)benzofuran.
References Cited (Backward Citations)
US3248401A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-04-28 | 1978-10-28 | 1979-04-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-04-28 | 1982-10-28 | 1983-04-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-04-28 | 1986-10-28 | 1987-04-29 | $7700.00 | Window Closed / Lapsed |